Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2934
Gene Symbol: GSN
GSN 		P06396 gelsolin Cellular structure 262 0.475 0.885 3.9E-11 0.400 strong 1.000 52 6 1990 2020
Entrez Id: 23621
Gene Symbol: BACE1
BACE1 		P56817 beta-secretase 1 Enzyme 120 0.559 0.769 0.88 0.100 None 1.000 52 0 2005 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 1.000 41 0 1993 2020
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.400 None 1.000 38 2 1997 2020
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2 		Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.100 None 1.000 37 0 2017 2020
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.100 None 1.000 37 0 2017 2020
Entrez Id: 4069
Gene Symbol: LYZ
LYZ 		P61626 lysozyme 178 0.526 0.846 3.4E-06 0.100 None 1.000 24 5 1988 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 19 0 2006 2019
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		P22303 acetylcholinesterase (Cartwright blood group) Enzyme 418 0.445 0.885 1.00 0.400 None 1.000 17 0 1996 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 15 0 2003 2018
Entrez Id: 3416
Gene Symbol: IDE
IDE 		P14735 insulin degrading enzyme Enzyme 71 0.604 0.577 6.6E-03 0.100 None 1.000 14 0 2004 2019
Entrez Id: 177
Gene Symbol: AGER
AGER 		Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.100 None 1.000 12 0 1999 2019
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		Q9NZC2 triggering receptor expressed on myeloid cells 2 239 0.519 0.769 3.3E-09 0.100 None 1.000 12 0 2010 2019
Entrez Id: 325
Gene Symbol: APCS
APCS 		P02743 amyloid P component, serum 141 0.531 0.808 3.2E-02 0.100 None 1.000 11 1 1987 2018
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.100 None 1.000 10 0 2011 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 10 0 1993 2020
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		P14136 glial fibrillary acidic protein 447 0.421 0.885 1.5E-06 0.100 None 1.000 10 0 2017 2019
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.100 None 1.000 10 0 2005 2020
Entrez Id: 1191
Gene Symbol: CLU
CLU 		P10909 clusterin 412 0.426 0.885 7.8E-05 0.090 None 1.000 9 3 2009 2018
Entrez Id: 7045
Gene Symbol: TGFBI
TGFBI 		Q15582 transforming growth factor beta induced Signaling 225 0.484 0.769 6.0E-08 0.090 None 1.000 9 1 1998 2019
Entrez Id: 4747
Gene Symbol: NEFL
NEFL 		P07196 neurofilament light 247 0.488 0.769 0.090 None 1.000 9 0 2017 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.080 None 1.000 8 0 2006 2019
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10 		O14672 ADAM metallopeptidase domain 10 224 0.489 0.846 1.00 0.080 None 1.000 8 0 2011 2019
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2 		Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 136 0.566 0.654 2.3E-03 0.080 None 1.000 8 0 2011 2019
Entrez Id: 336
Gene Symbol: APOA2
APOA2 		P02652 apolipoprotein A2 Transporter 77 0.582 0.769 4.5E-02 0.070 strong 1.000 7 0 2001 2019