Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.700 0.977 89 71 1991 2017
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase 274 0.448 0.724 3.5E-06 0.610 1.000 3 3 2009 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.500 0.972 38 7 1988 2016
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 235 0.463 0.690 3.3E-12 0.500 1.000 25 2 2009 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.500 1.000 15 6 1999 2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.500 1.000 13 3 2011 2016
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.400 0.955 23 0 1992 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.833 20 0 1995 2012
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 0.929 16 1 1995 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.400 1 2 2015 2015
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 564 0.373 0.931 0.49 0.350 1.000 6 0 1984 2013
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 481 0.391 0.862 1.0E-06 0.340 1.000 5 0 1995 2008
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box 2 transcription factor 251 0.459 0.759 0.73 0.340 1.000 5 0 2012 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.330 1.000 5 0 1996 2017
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 kinase; transferase 266 0.449 0.724 7.8E-02 0.320 1.000 3 0 1996 2011
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.320 1.000 3 0 2001 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 149 0.514 0.655 1.00 0.320 1.000 3 0 2011 2017
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 324 0.443 0.828 9.0E-11 0.320 1.000 3 0 2005 2011
Entrez Id: 5970
Gene Symbol: RELA
RELA
Q04206 RELA proto-oncogene, NF-kB subunit nucleic acid binding; transcription factor 245 0.456 0.828 1.00 0.310 1.000 2 0 2004 2011
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 386 0.435 0.759 1.00 0.310 1.000 2 0 1998 1998
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen nucleic acid binding 372 0.417 0.759 0.98 0.310 1.000 2 0 2004 2011
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
P21980 transglutaminase 2 transferase 171 0.499 0.690 7.0E-18 0.310 1.000 2 0 2006 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.310 2 0 2008 2012
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9
P11712 cytochrome P450 family 2 subfamily C member 9 129 0.542 0.759 1.8E-10 0.310 1.000 1 0 2006 2006
Entrez Id: 441478
Gene Symbol: NRARP
NRARP
Q7Z6K4 NOTCH regulated ankyrin repeat protein 7 0.834 0.069 0.22 0.300 1 0 2011 2011