Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.700 1.000 22 2 2004 2018
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.630 1.000 4 0 2011 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.600 1.000 25 0 2000 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.600 1.000 14 0 2001 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.530 1.000 5 0 2001 2018
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
P07333 colony stimulating factor 1 receptor 170 0.508 0.655 0.11 0.510 1.000 2 0 1992 2018
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A
O15550 lysine demethylase 6A transcription factor 175 0.543 0.724 1.00 0.500 1 0 2009 2009
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene 452 0.418 0.724 1.00 0.430 1.000 3 0 2018 2018
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor 293 0.464 0.586 5.5E-02 0.430 1.000 3 0 2018 2018
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene receptor tyrosine kinase 462 0.394 0.759 0.99 0.410 1.000 1 0 2018 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 1.000 73 1 2017 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule defense/immunity protein; receptor; signaling molecule 257 0.458 0.828 2.2E-02 0.400 1.000 31 0 2017 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 1.000 28 0 2017 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 1.000 19 0 2017 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.400 1.000 16 0 2017 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.400 1.000 12 1 2017 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 1.000 12 0 2017 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 1.000 11 0 2008 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.400 1.000 10 1 2017 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.400 1.000 10 0 2017 2018
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
O95467 P63092 P84996 Q5JWF2 GNAS complex locus enzyme modulator 394 0.443 0.793 0.71 0.400 0 0
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
P21912 succinate dehydrogenase complex iron sulfur subunit B oxidoreductase 207 0.513 0.690 3.4E-04 0.400 0 0
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
O14521 succinate dehydrogenase complex subunit D transfer/carrier protein 248 0.499 0.793 0.21 0.400 0 0
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.370 1.000 7 2 2017 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.360 1.000 6 0 2017 2018