Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8972
Gene Symbol: MGAM
MGAM
O43451 maltase-glucoamylase Enzyme 95 0.592 0.615 1.0E-35 0.100 None 1.000 96 0 2010 2020
Entrez Id: 6476
Gene Symbol: SI
SI
P14410 sucrase-isomaltase Enzyme 117 0.569 0.692 3.9E-60 0.100 None 1.000 95 0 2004 2020
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.400 None 1.000 75 0 2008 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.600 None 1.000 61 6 2008 2020
Entrez Id: 3416
Gene Symbol: IDE
IDE
P14735 insulin degrading enzyme Enzyme 71 0.604 0.577 6.6E-03 0.400 None 1.000 51 8 2000 2019
Entrez Id: 5950
Gene Symbol: RBP4
RBP4
P02753 retinol binding protein 4 Transporter 217 0.493 0.808 0.52 0.300 None 1.000 45 1 2006 2020
Entrez Id: 2864
Gene Symbol: FFAR1
FFAR1
O14842 free fatty acid receptor 1 G-protein coupled receptor 63 0.619 0.577 7.6E-04 0.100 None 1.000 39 2 2005 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 1.000 33 4 2006 2020
Entrez Id: 169792
Gene Symbol: GLIS3
GLIS3
Q8NEA6 GLIS family zinc finger 3 105 0.590 0.654 5.6E-08 0.500 None 1.000 30 10 2010 2019
Entrez Id: 5967
Gene Symbol: REG1A
REG1A
P05451 regenerating family member 1 alpha 264 0.467 0.846 1.3E-05 0.100 None 1.000 30 0 2006 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.100 None 1.000 29 0 1994 2020
Entrez Id: 139760
Gene Symbol: GPR119
GPR119
Q8TDV5 G protein-coupled receptor 119 G-protein coupled receptor 27 0.695 0.346 8.6E-03 0.100 None 1.000 27 0 2008 2020
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1
Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 325 0.453 0.846 0.14 0.300 None 1.000 27 0 2008 2020
Entrez Id: 5563
Gene Symbol: PRKAA2
PRKAA2
P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 317 0.456 0.846 3.5E-08 0.100 None 1.000 27 6 2006 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.700 None 1.000 26 3 2002 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.300 None 1.000 25 4 2001 2020
Entrez Id: 5564
Gene Symbol: PRKAB1
PRKAB1
Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 296 0.460 0.846 5.3E-03 0.100 None 1.000 25 0 2006 2020
Entrez Id: 2571
Gene Symbol: GAD1
GAD1
Q99259 glutamate decarboxylase 1 Enzyme 245 0.486 0.885 4.6E-02 0.100 None 1.000 24 0 1996 2019
Entrez Id: 2167
Gene Symbol: FABP4
FABP4
P15090 fatty acid binding protein 4 194 0.500 0.808 5.2E-05 0.100 None 1.000 23 0 2007 2019
Entrez Id: 51094
Gene Symbol: ADIPOR1
ADIPOR1
Q96A54 adiponectin receptor 1 Receptor 148 0.529 0.808 0.66 0.100 None 1.000 23 1 2004 2019
Entrez Id: 551
Gene Symbol: AVP
AVP
P01185 arginine vasopressin Signaling 454 0.437 0.846 7.4E-02 0.300 None 1.000 22 0 2008 2019
Entrez Id: 6484
Gene Symbol: ST3GAL4
ST3GAL4
Q11206 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 115 0.588 0.692 4.0E-02 0.100 None 1.000 21 0 2014 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 1.000 20 2 2001 2019
Entrez Id: 5891
Gene Symbol: MOK
MOK
Q9UQ07 MOK protein kinase Kinase 251 0.476 0.769 8.8E-22 0.400 None 1.000 20 2 2001 2019
Entrez Id: 8862
Gene Symbol: APLN
APLN
Q9ULZ1 apelin 226 0.497 0.769 0.46 0.100 None 1.000 20 2 2009 2019