Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2623
Gene Symbol: GATA1
GATA1
P15976 GATA binding protein 1 nucleic acid binding; transcription factor 212 0.510 0.690 0.95 0.400 0.989 93 0 2002 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 699 0.354 0.828 1.2E-09 0.400 0.884 48 1 1999 2016
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 oxidoreductase 456 0.406 0.931 0.13 0.400 0.955 45 0 1980 2016
Entrez Id: 1827
Gene Symbol: RCAN1
RCAN1
P53805 regulator of calcineurin 1 signaling molecule 62 0.630 0.586 1.6E-02 0.400 0.975 45 0 1996 2016
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B calcium-binding protein; signaling molecule 301 0.443 0.862 4.7E-02 0.400 0.950 22 0 1988 2013
Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1
P41440 solute carrier family 19 member 1 transporter 98 0.552 0.621 5.2E-06 0.400 0.778 12 1 2004 2014
Entrez Id: 1637
Gene Symbol: DCR
DCR
Down syndrome chromosome region 9 0.785 0.310 0.360 0.833 6 0 1994 2010
Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2
P32119 peroxiredoxin 2 oxidoreductase 116 0.535 0.759 8.6E-02 0.330 1.000 4 0 2001 2003
Entrez Id: 9588
Gene Symbol: PRDX6
PRDX6
P30041 peroxiredoxin 6 oxidoreductase 56 0.596 0.586 4.8E-05 0.310 2 0 2002 2003
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.310 1.000 2 0 2005 2006
Entrez Id: 7432
Gene Symbol: VIP
VIP
P01282 vasoactive intestinal peptide signaling molecule 152 0.526 0.759 3.9E-04 0.310 1.000 2 0 2006 2007
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
P20783 neurotrophin 3 signaling molecule 132 0.525 0.621 0.89 0.310 1.000 2 0 1998 2006
Entrez Id: 1859
Gene Symbol: DYRK1A
DYRK1A
Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A kinase; transferase 100 0.607 0.483 1.00 0.300 0.985 69 0 1996 2017
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha signaling molecule 274 0.456 0.828 1.4E-02 0.300 1 0 2006 2006
Entrez Id: 2946
Gene Symbol: GSTM2
GSTM2
P28161 glutathione S-transferase mu 2 126 0.517 0.793 3.5E-07 0.300 1 0 2002 2002
Entrez Id: 6175
Gene Symbol: RPLP0
RPLP0
P05388 ribosomal protein lateral stalk subunit P0 12 0.752 0.241 0.93 0.200 1 0 2016 2016
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein enzyme modulator 371 0.430 0.862 6.2E-02 0.100 0.968 66 1 1988 2017
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 runt related transcription factor 1 nucleic acid binding; transcription factor 248 0.467 0.690 0.88 0.100 0.905 23 0 1997 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.100 1.000 23 0 1995 2015
Entrez Id: 5069
Gene Symbol: PAPPA
PAPPA
Q13219 pappalysin 1 61 0.614 0.448 0.18 0.100 0.842 20 0 1996 2016
Entrez Id: 174
Gene Symbol: AFP
AFP
P02771 alpha fetoprotein transfer/carrier protein 181 0.502 0.724 1.2E-11 0.100 0.947 19 0 1986 2014
Entrez Id: 2114
Gene Symbol: ETS2
ETS2
P15036 ETS proto-oncogene 2, transcription factor nucleic acid binding; signaling molecule; transcription factor 90 0.557 0.690 1.00 0.100 1.000 18 0 1987 2010
Entrez Id: 875
Gene Symbol: CBS
CBS
P0DN79 P35520 cystathionine-beta-synthase hydrolase; isomerase; lyase 197 0.503 0.793 2.8E-05 0.100 0.941 18 1 1990 2012
Entrez Id: 4548
Gene Symbol: MTR
MTR
Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 196 0.493 0.724 2.6E-10 0.100 0.800 16 1 2003 2015
Entrez Id: 102724560
Gene Symbol: CBSL
CBSL
P0DN79 P35520 cystathionine-beta-synthase like hydrolase; isomerase; lyase 70 0.592 0.552 0.100 0.938 16 0 1990 2012