Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.700 0.972 438 7 1988 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.500 0.929 133 5 1997 2017
Entrez Id: 3020
Gene Symbol: H3F3A
H3F3A
P84243 H3 histone family member 3A nucleic acid binding 30 0.667 0.310 0.13 0.500 0.941 19 1 2012 2017
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.400 0.958 266 2 1992 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 0.942 233 53 1990 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.990 105 1 1992 2017
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
O43490 prominin 1 membrane traffic protein 306 0.450 0.793 2.4E-18 0.400 0.974 79 0 2006 2018
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 494 0.386 0.897 1.0E-16 0.400 0.970 68 0 1988 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.400 0.951 44 0 2000 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.400 0.968 32 0 1998 2016
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.400 1.000 30 0 1994 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.400 1.000 29 0 1996 2017
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha 278 0.456 0.690 1.00 0.400 1.000 27 0 1995 2018
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
P36222 chitinase 3 like 1 167 0.502 0.793 8.5E-06 0.400 0.938 19 0 2003 2016
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.400 1.000 19 0 1991 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.400 1.000 18 0 1991 2016
Entrez Id: 4194
Gene Symbol: MDM4
MDM4
O15151 MDM4, p53 regulator nucleic acid binding 159 0.501 0.724 1.00 0.400 1.000 12 0 2000 2018
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.400 0.909 12 0 2007 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.400 0.900 11 0 2011 2016
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 205 0.477 0.690 0.94 0.390 1.000 10 0 2009 2016
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 signaling molecule 461 0.399 0.828 1.2E-03 0.380 1.000 9 0 1991 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.380 1.000 9 0 1986 2016
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 564 0.373 0.931 0.49 0.370 1.000 7 0 1987 2009
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
P07858 cathepsin B enzyme modulator; hydrolase; protease 192 0.490 0.828 3.3E-11 0.360 1.000 7 0 1995 2012
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch 2 287 0.474 0.724 1.00 0.360 1.000 7 0 2009 2016