Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.010 None 1.000 1 0 2016 2016
Entrez Id: 6598
Gene Symbol: SMARCB1
SMARCB1
Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 448 0.434 0.846 1.00 0.100 None 1.000 1 1 2010 2010
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 Kinase 372 0.435 0.808 0.99 0.120 None 1.000 41 64 1992 2018
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.100 None 0 1
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.110 None 1.000 31 29 1994 2017
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.100 None 1.000 139 215 1990 2018
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.180 None 1.000 172 59 1994 2017
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.100 None 1.000 71 103 1989 2018
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
O00255 menin 1 364 0.444 0.808 1.00 0.050 None 1.000 5 106 1999 2010
Entrez Id: 23405
Gene Symbol: DICER1
DICER1
Q9UPY3 dicer 1, ribonuclease III Enzyme 302 0.446 0.846 1.00 0.120 None 1.000 13 90 2009 2016
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.100 None 1.000 2 4 2011 2014
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.180 None 1.000 19 23 2011 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.100 None 1.000 106 133 1999 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.110 None 1.000 191 331 1994 2018
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.100 None 1.000 36 92 1998 2017
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.100 None 1.000 72 31 1998 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.110 None 1.000 127 71 1995 2018
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5315
Gene Symbol: PKM
PKM
P14618 pyruvate kinase M1/2 Kinase 237 0.482 0.808 0.85 0.010 None 1.000 1 0 2018 2018
Entrez Id: 25859
Gene Symbol: PART1
PART1
prostate androgen-regulated transcript 1 250 0.483 0.885 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.110 None 1.000 113 124 1995 2018
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.100 None 1.000 110 293 2007 2017
Entrez Id: 2271
Gene Symbol: FH
FH
P07954 fumarate hydratase Enzyme 231 0.489 0.846 8.8E-02 0.150 None 1.000 75 63 1997 2019
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CDKN2B antisense RNA 1 213 0.491 0.769 0.100 None 0 1
Entrez Id: 4286
Gene Symbol: MITF
MITF
O75030 melanocyte inducing transcription factor 244 0.499 0.808 0.98 0.100 None 1.000 22 1 1987 2016