Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 22 0.367 0.923 9.2E-29 0.800 strong 0.986 800 874 1990 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 68 0.379 0.846 2.4E-25 0.800 strong 0.993 714 1160 1990 2020
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
O43502 RAD51 paralog C 5 0.533 0.692 6.2E-14 0.500 None 1.000 20 14 2010 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.500 None 0.941 5 2 1994 2019
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 48 0.485 0.769 3.0E-19 0.460 None 0.970 26 17 2007 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 48 0.460 0.808 1.2E-24 0.460 None 1.000 25 6 2003 2019
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D
O75771 RAD51 paralog D 5 0.674 0.385 1.1E-09 0.420 None 1.000 17 7 2010 2018
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 15 0.507 0.731 6.2E-17 0.410 None 1.000 13 9 2005 2019
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 7 0.597 0.538 1.4E-24 0.400 None 1.000 12 5 2004 2017
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
P49959 MRE11 homolog, double strand break repair nuclease 21 0.527 0.808 1.3E-12 0.400 None 1.000 1 1 2003 2016
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 15 0.467 0.808 2.2E-16 0.400 None 1.000 1 2 2003 2014
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 44 0.374 0.885 5.6E-47 0.160 None 0.875 2 6 2000 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 15 0.399 0.808 3.4E-05 0.150 None 1.000 0 1 2000 2015
Entrez Id: 160140
Gene Symbol: C11orf65
C11orf65
Q8NCR3 chromosome 11 open reading frame 65 32 0.670 0.462 2.0E-14 0.100 None 1.000 1 4 2016 2016
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B
O15315 RAD51 paralog B 2 0.556 0.769 2.1E-15 0.100 None 1.000 1 1 2016 2016
Entrez Id: 140660
Gene Symbol: RPL21P4
RPL21P4
ribosomal protein L21 pseudogene 4 1 1.000 0.192 0.100 None 0 1
Entrez Id: 84142
Gene Symbol: ABRAXAS1
ABRAXAS1
Q6UWZ7 abraxas 1, BRCA1 A complex subunit 3 0.760 0.269 5.1E-07 0.100 None 0 1