Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 0.929 14 0 2004 2019
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.100 None 1.000 13 0 2008 2019
Entrez Id: 51115
Gene Symbol: RMDN1
RMDN1
Q96DB5 regulator of microtubule dynamics 1 123 0.546 0.769 5.9E-10 0.100 None 1.000 10 0 2006 2019
Entrez Id: 151393
Gene Symbol: RMDN2
RMDN2
Q96LZ7 regulator of microtubule dynamics 2 137 0.531 0.769 4.4E-24 0.100 None 1.000 10 0 2006 2019
Entrez Id: 55177
Gene Symbol: RMDN3
RMDN3
Q96TC7 regulator of microtubule dynamics 3 134 0.534 0.769 5.2E-05 0.100 None 1.000 10 0 2006 2019
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
P09917 arachidonate 5-lipoxygenase Enzyme 342 0.447 0.885 1.2E-06 0.070 None 1.000 7 0 2014 2018
Entrez Id: 7314
Gene Symbol: UBB
UBB
P0CG47 ubiquitin B Nucleic acid binding 70 0.599 0.615 1.7E-02 0.070 None 1.000 7 0 2003 2011
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.070 None 1.000 7 0 2014 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.070 None 0.857 7 0 2004 2019
Entrez Id: 5524
Gene Symbol: PTPA
PTPA
Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 245 0.480 0.846 0.99 0.060 None 1.000 6 0 2009 2019
Entrez Id: 5967
Gene Symbol: REG1A
REG1A
P05451 regenerating family member 1 alpha 264 0.467 0.846 1.3E-05 0.060 None 1.000 6 0 2003 2019
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.060 None 1.000 6 0 2002 2019
Entrez Id: 140683
Gene Symbol: BPIFA2
BPIFA2
Q96DR5 BPI fold containing family A member 2 80 0.608 0.808 8.0E-07 0.050 None 1.000 5 0 2003 2019
Entrez Id: 5623
Gene Symbol: PSPN
PSPN
O60542 persephin Signaling 70 0.608 0.769 1.1E-04 0.050 None 1.000 5 0 2003 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.050 None 1.000 5 0 2014 2018
Entrez Id: 4477
Gene Symbol: MSMB
MSMB
P08118 microseminoprotein beta Signaling 195 0.498 0.846 1.6E-02 0.050 None 1.000 5 0 2003 2019
Entrez Id: 9451
Gene Symbol: EIF2AK3
EIF2AK3
Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 231 0.501 0.808 2.8E-03 0.050 None 1.000 5 0 2015 2019
Entrez Id: 10247
Gene Symbol: RIDA
RIDA
P52758 reactive intermediate imine deaminase A homolog 72 0.606 0.769 6.8E-02 0.050 None 1.000 5 0 2003 2019
Entrez Id: 6814
Gene Symbol: STXBP3
STXBP3
O00186 syntaxin binding protein 3 Transporter 69 0.610 0.769 5.2E-05 0.050 None 1.000 5 0 2003 2019
Entrez Id: 5723
Gene Symbol: PSPH
PSPH
P78330 phosphoserine phosphatase Enzyme 114 0.570 0.808 9.7E-04 0.050 None 1.000 5 0 2003 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.040 None 1.000 4 0 2013 2019
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
Q9NZC2 triggering receptor expressed on myeloid cells 2 239 0.519 0.769 3.3E-09 0.040 None 1.000 4 0 2017 2018
Entrez Id: 406921
Gene Symbol: MIR132
MIR132
microRNA 132 222 0.485 0.846 0.040 None 1.000 4 0 2015 2018
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 310 0.457 0.885 6.1E-02 0.030 None 1.000 3 0 2010 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.030 None 1.000 3 0 2002 2012