Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 221037
Gene Symbol: JMJD1C
JMJD1C
Q15652 jumonji domain containing 1C 214 0.517 0.769 1.00 0.400 None 1.000 2 9 2009 2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 316 0.471 0.769 0.77 0.150 None 0.800 5 3 2009 2019
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor Signaling 306 0.466 0.769 5.6E-04 0.120 None 1.000 3 3 2011 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.030 None 1.000 3 3 2005 2018
Entrez Id: 221035
Gene Symbol: REEP3
REEP3
Q6NUK4 receptor accessory protein 3 Transporter 22 0.792 0.308 1.5E-02 0.110 None 1.000 2 3 2012 2018
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 Transcription factor 226 0.489 0.731 9.0E-03 0.020 None 1.000 2 3 2011 2018
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
P34972 cannabinoid receptor 2 G-protein coupled receptor 197 0.509 0.846 6.5E-06 0.010 None 1.000 1 3 2015 2015
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
Q2KHT3 C-type lectin domain containing 16A 67 0.612 0.654 0.28 0.010 None 1.000 1 3 2010 2010
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.200 None 1.000 17 2 2005 2015
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 540 0.389 0.885 5.5E-02 0.180 None 0.889 9 2 2004 2015
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.050 None 1.000 5 2 2004 2018
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.050 None 0.800 5 2 2004 2015
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.040 None 0.750 4 2 2005 2015
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase non-receptor type 2 134 0.538 0.692 1.00 0.130 None 1.000 4 2 2010 2015
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
Q9ULJ6 zinc finger MIZ-type containing 1 96 0.588 0.615 1.00 0.110 None 1.000 3 2 2014 2018
Entrez Id: 400757
Gene Symbol: C1orf141
C1orf141
Q5JVX7 chromosome 1 open reading frame 141 30 0.691 0.385 3.2E-03 0.100 None 1.000 1 2 2015 2015
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
Q9NZ08 endoplasmic reticulum aminopeptidase 1 Enzyme 156 0.556 0.692 2.1E-26 0.010 None 1.000 1 2 2011 2011
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
P07550 adrenoceptor beta 2 G-protein coupled receptor 387 0.442 0.923 0.53 0.010 None 1.000 1 2 2009 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.974 39 1 1995 2020
Entrez Id: 79679
Gene Symbol: VTCN1
VTCN1
Q7Z7D3 V-set domain containing T cell activation inhibitor 1 Enzyme modulator 139 0.529 0.692 1.4E-12 0.150 None 0.800 5 1 2009 2015
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.330 None 1.000 4 1 2006 2010
Entrez Id: 4026
Gene Symbol: LPP
LPP
Q93052 LIM domain containing preferred translocation partner in lipoma Enzyme modulator 131 0.543 0.769 7.2E-03 0.320 None 0.667 3 1 2009 2012
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.030 None 1.000 3 1 2002 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.020 None 0.500 2 1 2010 2015
Entrez Id: 79722
Gene Symbol: ANKRD55
ANKRD55
Q3KP44 ankyrin repeat domain 55 46 0.650 0.462 6.8E-08 0.110 None 1.000 2 1 2015 2015