Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.310 Biomarker disease CTD_human Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes. 18698320 2009
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Biomarker disease CTD_human Adrenocorticotropic hormone and cortisol plasma levels directly correlate with childhood neglect and depression measures in addicted patients. 18201294 2008
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.310 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.310 Biomarker disease CTD_human Intracerebroventricular corticotropin-releasing factor increases limbic glucose metabolism and has social context-dependent behavioral effects in nonhuman primates. 12438692 2002
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1
0.300 Biomarker disease CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079 2018
Entrez Id: 7038
Gene Symbol: TG
TG
0.300 Biomarker disease CTD_human Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice. 30373627 2018
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.300 Biomarker disease CTD_human DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders. 29643356 2018
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
0.300 Biomarker disease CTD_human Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses. 26860412 2017
Entrez Id: 6403
Gene Symbol: SELP
SELP
0.300 Biomarker disease CTD_human Platelet hyperactivity, neurobehavioral symptoms and depression among Indian women chronically exposed to low level of arsenic. 25451969 2014
Entrez Id: 6281
Gene Symbol: S100A10
S100A10
0.300 Biomarker disease CTD_human Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. 21682946 2012
Entrez Id: 2739
Gene Symbol: GLO1
GLO1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 2782
Gene Symbol: GNB1
GNB1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 23705
Gene Symbol: CADM1
CADM1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.300 Biomarker disease CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
0.300 Biomarker disease CTD_human 5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques. 21871532 2011
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
0.300 Biomarker disease CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 2931
Gene Symbol: GSK3A
GSK3A
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. 20534517 2010
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.300 Biomarker disease CTD_human Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. 18458677 2009
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Factors influencing long-term changes in mental health after interferon-alpha treatment of chronic hepatitis C. 19691667 2009
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.300 Biomarker disease CTD_human Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. 19605942 2009
Entrez Id: 5444
Gene Symbol: PON1
PON1
0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.300 Biomarker disease CTD_human Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain. 19356723 2009
Entrez Id: 51738
Gene Symbol: GHRL
GHRL
0.300 Biomarker disease CTD_human Ghrelin, paraoxonase and arylesterase levels in depressive patients before and after citalopram treatment. 19272368 2009