Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7533
Gene Symbol: YWHAH
YWHAH 		0.300 Therapeutic disease CTD_human 14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy. 18342293 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.300 Biomarker disease CTD_human Investigation of ocular neovascularization-related genes and oxidative stress in diabetic rat eye tissues after resveratrol treatment. 22191573 2012
Entrez Id: 7351
Gene Symbol: UCP2
UCP2 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 7351
Gene Symbol: UCP2
UCP2 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_mouse Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice. 21078376 2011
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		0.300 Therapeutic disease CTD_human Polyethylene glycolated recombinant TNF receptor I improves insulitis and reduces incidence of spontaneous and cyclophosphamide-accelerated diabetes in nonobese diabetic mice. 12193562 2002
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism. 20388520 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Protective effects of chronic resveratrol treatment on vascular inflammatory injury in streptozotocin-induced type 2 diabetic rats: Role of NF-kappa B signaling. 24513509 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Polyethylene glycolated recombinant TNF receptor I improves insulitis and reduces incidence of spontaneous and cyclophosphamide-accelerated diabetes in nonobese diabetic mice. 12193562 2002
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in stz diabetic rats. 12123627 2002
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis. 22138235 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. 19478208 2009
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2 		0.300 Biomarker disease CTD_human Altered matrix metalloproteinases and tissue inhibitors of metalloproteinases in embryos from diabetic rats during early organogenesis. 21963884 2011
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		0.300 Biomarker disease CTD_human Altered matrix metalloproteinases and tissue inhibitors of metalloproteinases in embryos from diabetic rats during early organogenesis. 21963884 2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease CTD_human Protective effect of Gui Qi mixture on the progression of diabetic nephropathy in rats. 17177138 2006
Entrez Id: 412
Gene Symbol: STS
STS 		0.300 Therapeutic disease CTD_human Hepatic overexpression of steroid sulfatase ameliorates mouse models of obesity and type 2 diabetes through sex-specific mechanisms. 24497646 2014
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1 		0.300 Biomarker disease CTD_human Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets. 10900012 2000
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Therapeutic disease CTD_human MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. 15855331 2005
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker disease CTD_human MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. 15855331 2005
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Therapeutic disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013