| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | AlteredExpression | disease | BEFREE | Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia. | 14744462 | 2004 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Additional evidence for a role of serotonin (5-HT) in the pathogenesis of suicidal behavior is provided by a recent report that the 5-HT2A (HTR2A) T102C polymorphism was associated with suicidality in patients with major depression. | 15469201 | 2004 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The results demonstrated that the -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene was unlikely to have a major role in therapeutic response to fluvoxamine in Japanese patients with major depressive disorder. | 12422060 | 2002 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | These results suggest that variation in the 5-HT2A receptor gene may play a role in the development of major depression with seasonal pattern and support the existence of a genetic and etiological heterogeneity underlying the diagnosis of major depression. | 11317230 | 2001 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Overall our results suggest that the investigated 5-HT2A and 5-HTTLPR polymorphisms are not major susceptibility factors in the etiology of major depression. | 11311507 | 2001 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The 102T/C polymorphism of the 5-HT(2A) receptor gene was analyzed in 159 patients with major depression (DSM-IV criteria) and 164 unrelated and healthy controls using a case control design. | 11803534 | 2001 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Recent studies have shown an association of allele C of the 5-HT2A-T102C polymorphism with suicidal ideation in patients with major depression. | 11121191 | 2000 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Our results suggest that the 102T/C polymorphism in 5-HT2A receptor gene is primarily associated with suicidal ideation in patients with major depression.Am.J. Med.Genet.(Neuropsychiatr.Genet.)96:56-60, 2000. | 10686553 | 2000 |