Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1 		0.300 Therapeutic group CTD_human Protective effects of pituitary adenylate cyclase activating polypeptide against neurotoxic agents. 29604313 2018
Entrez Id: 54583
Gene Symbol: EGLN1
EGLN1 		0.300 Biomarker group CTD_human Genetic p23 knockdown was found to result in decreases in steady-state PHD2 protein and activity and reduced susceptibility to MPP<sup>+</sup> neurotoxicity. 29471019 2018
Entrez Id: 10728
Gene Symbol: PTGES3
PTGES3 		0.300 Biomarker group CTD_human Genetic p23 knockdown was found to result in decreases in steady-state PHD2 protein and activity and reduced susceptibility to MPP<sup>+</sup> neurotoxicity. 29471019 2018
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD 		0.300 Biomarker group CTD_human Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ. 22512859 2012
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		0.300 Biomarker group CTD_human It is suggested that Caspase-3 siRNA may reduce the neurotoxicity induced by aluminum to a certain extent. 21972528 2011
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Therapeutic group CTD_human Recombinant paraoxonase 1 protects against sarin and soman toxicity following microinstillation inhalation exposure in guinea pigs. 21329748 2011
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Therapeutic group CTD_human Post-exposure therapy with recombinant human BuChE following percutaneous VX challenge in guinea-pigs. 21620937 2011
Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5 		0.300 Therapeutic group CTD_human Eighty-nine percent of CYP3A5 expressers experienced neurotoxicity versus 100% of non-expressers (P = 0.03). 21225912 2011
Entrez Id: 83716
Gene Symbol: CRISPLD2
CRISPLD2 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		0.300 Therapeutic group CTD_human This outcome is associated with an increased basal resistance, but more so, an enhanced Nrf2 response to lesioning that attenuated the ensuing neurotoxicity. 20211941 2010
Entrez Id: 885
Gene Symbol: CCK
CCK 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 7051
Gene Symbol: TGM1
TGM1 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 27040
Gene Symbol: LAT
LAT 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 6489
Gene Symbol: ST8SIA1
ST8SIA1 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 120
Gene Symbol: ADD3
ADD3 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 5023
Gene Symbol: P2RX1
P2RX1 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 915
Gene Symbol: CD3D
CD3D 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		0.300 Therapeutic group CTD_human These results support the protective role of DT-diaphorase against aminochrome neurotoxicity in dopaminergic neurons containing neuromelanin and show that Nq6 and Nq7 siRNA are very useful tools to study the role of DT-diaphorase in aminochrome metabolism. 20849151 2010
Entrez Id: 6430
Gene Symbol: SRSF5
SRSF5 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 6039
Gene Symbol: RNASE6
RNASE6 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 2570
Gene Symbol: GABRR2
GABRR2 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP 		0.300 Biomarker group CTD_human Blood gene expression markers to detect and distinguish target organ toxicity. 19784758 2010
Entrez Id: 147
Gene Symbol: ADRA1B
ADRA1B 		0.300 Biomarker group CTD_human Lack of alpha 1b-adrenergic receptor protects against epileptic seizures. 19125850 2009