Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Biomarker disease CTD_human Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors. 2317787 1990
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human The molecular basis of Turcot's syndrome. 7661930 1995
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.300 Therapeutic disease CTD_human Interleukin-2 gene therapy in a patient with glioblastoma. 7719933 1995
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 GeneticVariation disease BEFREE In this study, we assessed p53 mutations and EGFR expression in the giant cell glioblastoma. 9370234 1997
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.310 AlteredExpression disease BEFREE p53 mutations versus EGF receptor expression in giant cell glioblastomas. 9370234 1997
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.020 GeneticVariation disease BEFREE None of the giant cell glioblastomas showed a homozygous deletion of PTEN orp16, or amplification of MDM2. 10068201 1999
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.300 Biomarker disease ORPHANET Over-representation of PPARgamma sequence variants in sporadic cases of glioblastoma multiforme: preliminary evidence for common low penetrance modifiers for brain tumour risk in the general population. 10851250 2000
Entrez Id: 699
Gene Symbol: BUB1
BUB1 		0.010 Biomarker disease BEFREE We further screened hBUB1 in 18 cases of giant cell glioblastoma, a variant characterized by a predominance of bizarre, multinucleated giant cells. 11355300 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 Biomarker disease BEFREE This article gives an outline of molecular biological approaches to analysis of neurological disorders such as giant cell glioblastoma (GGBM) and amyotrophic lateral sclerosis (ALS), and their respective animal models: p53 knockout mice for GGBM and mutant superoxide dismutase-1 transgenic mice for ALS. 12564775 2002
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		0.010 GeneticVariation disease BEFREE This article gives an outline of molecular biological approaches to analysis of neurological disorders such as giant cell glioblastoma (GGBM) and amyotrophic lateral sclerosis (ALS), and their respective animal models: p53 knockout mice for GGBM and mutant superoxide dismutase-1 transgenic mice for ALS. 12564775 2002
Entrez Id: 5747
Gene Symbol: PTK2
PTK2 		0.300 Biomarker disease CTD_human Geldanamycin inhibits migration of glioma cells in vitro: a potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion. 12811834 2003
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.300 Biomarker disease CTD_human Geldanamycin inhibits migration of glioma cells in vitro: a potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion. 12811834 2003
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1 		0.300 Biomarker disease CTD_human Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers. 15341671 2004
Entrez Id: 7052
Gene Symbol: TGM2
TGM2 		0.300 Therapeutic disease CTD_human Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. 16170020 2005
Entrez Id: 7052
Gene Symbol: TGM2
TGM2 		0.300 Biomarker disease CTD_human Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. 16170020 2005
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.310 Biomarker disease CTD_human Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. 16598420 2006
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.300 Biomarker disease CTD_human Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. 16598420 2006
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker disease CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833 2006
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.300 Biomarker disease CTD_human Expression of glutathione S-transferase T1 (GSTT1) in human brain tumours. 16874663 2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		0.300 Biomarker disease CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833 2006
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.300 Biomarker disease CTD_human Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. 16598420 2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.300 Biomarker disease CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 Biomarker disease ORPHANET Long-term survival with glioblastoma multiforme. 17785346 2007
Entrez Id: 26136
Gene Symbol: TES
TES 		0.300 Biomarker disease CTD_human Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. 16909125 2007
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3 		0.300 Biomarker disease CTD_human Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. 16909125 2007