Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.040 GeneticVariation disease BEFREE BRAF V600E mutation has been identified in up to 2/3 of pleomorphic xanthoastrocytomas (PXAs), World Health Organization grade II, as well as in varying percentages of PXAs with anaplastic features (PXA-A), gangliogliomas, extracerebellar pilocytic astrocytomas, and, rarely, giant cell glioblastoma multiforme (GC-GBMs). 23552385 2013
Entrez Id: 546
Gene Symbol: ATRX
ATRX 		0.010 Biomarker disease BEFREE ATRX loss was detected immunohistochemically in 19% of giant cell glioblastomas, but absent in 17 gliosarcomas. 26443480 2016
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker disease CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833 2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		0.300 Biomarker disease CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833 2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.300 Biomarker disease CTD_human A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines. 16356833 2006
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.510 Biomarker disease ORPHANET A study of clinico-pathological parameters and O⁶-methylguanine DNA methyltransferase (MGMT) promoter methylation status in the prognostication of gliosarcoma. 22380407 2012
Entrez Id: 8842
Gene Symbol: PROM1
PROM1 		0.300 Biomarker disease CTD_human Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. 18829568 2008
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		0.310 Biomarker disease ORPHANET An integrated genomic analysis of human glioblastoma multiforme. 18772396 2008
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.300 Therapeutic disease CTD_human Cisplatin restores TRAIL apoptotic pathway in glioblastoma-derived stem cells through up-regulation of DR5 and down-regulation of c-FLIP. 21877938 2011
Entrez Id: 8425
Gene Symbol: LTBP4
LTBP4 		0.300 Biomarker disease CTD_human Clonal evolution of glioblastoma under therapy. 27270107 2016
Entrez Id: 26136
Gene Symbol: TES
TES 		0.300 Biomarker disease CTD_human Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. 16909125 2007
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3 		0.300 Biomarker disease CTD_human Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. 16909125 2007
Entrez Id: 1848
Gene Symbol: DUSP6
DUSP6 		0.300 Biomarker disease CTD_human Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas. 21499306 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 Biomarker disease CTD_human EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling. 26455392 2015
Entrez Id: 23476
Gene Symbol: BRD4
BRD4 		0.300 Biomarker disease CTD_human EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling. 26455392 2015
Entrez Id: 1513
Gene Symbol: CTSK
CTSK 		0.300 Biomarker disease CTD_human Expression analysis of all protease genes reveals cathepsin K to be overexpressed in glioblastoma. 25356585 2014
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Biomarker disease CTD_human Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors. 2317787 1990
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.300 Biomarker disease CTD_human Expression of glutathione S-transferase T1 (GSTT1) in human brain tumours. 16874663 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 GeneticVariation disease BEFREE Fifty-nine percent of gcGB samples but only 18% of the GB samples showed p53 mutations. 20467329 2010
Entrez Id: 5747
Gene Symbol: PTK2
PTK2 		0.300 Biomarker disease CTD_human Geldanamycin inhibits migration of glioma cells in vitro: a potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion. 12811834 2003
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.300 Biomarker disease CTD_human Geldanamycin inhibits migration of glioma cells in vitro: a potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion. 12811834 2003
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		0.500 SomaticCausalMutation disease ORPHANET Genomics informs glioblastoma biology. 24071842 2013
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.010 GeneticVariation disease BEFREE Germline mutation p.N363K in POLE is associated with an increased risk of colorectal cancer and giant cell glioblastoma. 30368636 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		0.300 Biomarker disease CTD_human Glial cell-line derived neurotrophic factor (GDNF) family of ligands confer chemoresistance in a ligand-specific fashion in malignant gliomas. 19138852 2009
Entrez Id: 8842
Gene Symbol: PROM1
PROM1 		0.300 Biomarker disease CTD_human Glioblastoma formation from cell population depleted of Prominin1-expressing cells. 19718438 2009