×
Entrez Id:
9971
Gene Symbol:
NR1H4
NR1H4
0.300
Therapeutic
phenotype
CTD_human
Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis.
30996006
2019
×
Entrez Id:
63036
Gene Symbol:
CELA2A
CELA2A
0.300
Biomarker
phenotype
CTD_human
CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation.
31358993
2019
×
Entrez Id:
10155
Gene Symbol:
TRIM28
TRIM28
0.300
Biomarker
phenotype
CTD_human
Knockdown of TRIM28 inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration.
31351049
2019
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Using the Apolipoprotein E Knock-Out Mouse Model to Define Atherosclerotic Plaque Changes Induced by Low Dose Arsenic.
30376133
2018
×
Entrez Id:
3949
Gene Symbol:
LDLR
LDLR
0.300
Biomarker
phenotype
CTD_human
Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis.
28899902
2017
×
Entrez Id:
3949
Gene Symbol:
LDLR
LDLR
0.300
Therapeutic
phenotype
CTD_human
Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis.
28899902
2017
×
Entrez Id:
5819
Gene Symbol:
NECTIN2
NECTIN2
0.300
Biomarker
phenotype
CTD_human
Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration.
28062492
2017
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Sinigrin attenuates the progression of atherosclerosis in ApoE-/- mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression.
28483571
2017
×
Entrez Id:
1071
Gene Symbol:
CETP
CETP
0.300
Therapeutic
phenotype
CTD_human
A novel atheroprotective role of MF59-like adjuvant when co-administered with CETP vaccine in rabbit model of atherosclerosis.
28096968
2016
×
Entrez Id:
602
Gene Symbol:
BCL3
BCL3
0.300
Biomarker
phenotype
CTD_human
An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis.
25374339
2015
×
Entrez Id:
5444
Gene Symbol:
PON1
PON1
0.300
Biomarker
phenotype
CTD_human
Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population.
26241956
2015
×
Entrez Id:
3949
Gene Symbol:
LDLR
LDLR
0.300
Therapeutic
phenotype
CTD_human
Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits.
25619500
2015
×
Entrez Id:
5444
Gene Symbol:
PON1
PON1
0.300
Therapeutic
phenotype
CTD_human
Association between Paraoxonase 1 (PON1) Polymorphisms and the Risk of Acute Coronary Syndrome in a North African Population.
26241956
2015
×
Entrez Id:
3949
Gene Symbol:
LDLR
LDLR
0.300
Biomarker
phenotype
CTD_human
Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits.
25619500
2015
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Pulmonary exposure to particles from diesel exhaust, urban dust or single-walled carbon nanotubes and oxidatively damaged DNA and vascular function in apoE(-/-) mice.
23148895
2014
×
Entrez Id:
6348
Gene Symbol:
CCL3
CCL3
0.300
Biomarker
phenotype
CTD_human
27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes.
24370436
2014
×
Entrez Id:
3269
Gene Symbol:
HRH1
HRH1
0.300
Biomarker
phenotype
CTD_human
Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.
25020133
2014
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.
25020133
2014
×
Entrez Id:
6351
Gene Symbol:
CCL4
CCL4
0.300
Biomarker
phenotype
CTD_human
27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes.
24370436
2014
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice.
24330719
2013
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1.
24017971
2013
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Cigarette smoke induces molecular responses in respiratory tissues of ApoE(-/-) mice that are progressively deactivated upon cessation.
24096154
2013
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Inhibitory effects of myricitrin on oxidative stress-induced endothelial damage and early atherosclerosis in ApoE-/- mice.
23639522
2013
×
Entrez Id:
196
Gene Symbol:
AHR
AHR
0.300
Biomarker
phenotype
CTD_human
Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice.
22228805
2012
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.300
Biomarker
phenotype
CTD_human
Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice.
22228805
2012