Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice. 16326803 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Sarcomeric hypertrophic cardiomyopathy: genetic profile in a Portuguese population. 22857948 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 GeneticVariation disease CLINVAR Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy. 12707239 2003
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Different functional properties of troponin T mutants that cause dilated cardiomyopathy. 12923187 2003
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform. 15623536 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Multiple gene mutations, not the type of mutation, are the modifier of left ventricle hypertrophy in patients with hypertrophic cardiomyopathy. 23283745 2013
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 GeneticVariation disease UNIPROT Sudden death due to troponin T mutations. 9060892 1997
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype. 21551322 2011
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 GeneticVariation disease CLINVAR Novel missense mutation in cardiac troponin T gene found in Japanese patient with hypertrophic cardiomyopathy. 9140840 1997
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction. 14722098 2004
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. 17932326 2007
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR IMAGE CARDIO MED: Inducible malignant ventricular tachyarrhythmia in a patient with genotyped hypertrophic cardiomyopathy in absence of left ventricular hypertrophy or enlargement. 19487599 2009
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy. 12186860 2002
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 GeneticVariation disease UNIPROT Novel missense mutation in cardiac troponin T gene found in Japanese patient with hypertrophic cardiomyopathy. 9140840 1997
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Late gadolinium enhancement cardiovascular magnetic resonance in genotyped hypertrophic cardiomyopathy with normal phenotype. 19087273 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Shared genetic causes of cardiac hypertrophy in children and adults. 18403758 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 GeneticVariation disease CLINVAR Sarcomeric hypertrophic cardiomyopathy: genetic profile in a Portuguese population. 22857948 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Sudden death due to troponin T mutations. 9060892 1997
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. 22517884 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 Biomarker disease CTD_human
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR The chromosome, its anatomy, and its aberrations. 2003160 1991
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 GeneticVariation disease UNIPROT Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. 8205619 1994
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Exome Sequencing Identifies Pathogenic and Modifier Mutations in a Child With Sporadic Dilated Cardiomyopathy. 26656454 2015
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 Biomarker disease MGD
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.900 CausalMutation disease CLINVAR Whole exome sequencing identifies a troponin T mutation hot spot in familial dilated cardiomyopathy. 24205113 2013