×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
CLINVAR
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy.
12707239
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Different functional properties of troponin T mutants that cause dilated cardiomyopathy.
12923187
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform.
15623536
2005
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Multiple gene mutations, not the type of mutation, are the modifier of left ventricle hypertrophy in patients with hypertrophic cardiomyopathy.
23283745
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype.
21551322
2011
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
CLINVAR
Novel missense mutation in cardiac troponin T gene found in Japanese patient with hypertrophic cardiomyopathy.
9140840
1997
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction.
14722098
2004
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.
17932326
2007
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
IMAGE CARDIO MED: Inducible malignant ventricular tachyarrhythmia in a patient with genotyped hypertrophic cardiomyopathy in absence of left ventricular hypertrophy or enlargement.
19487599
2009
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy.
12186860
2002
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Late gadolinium enhancement cardiovascular magnetic resonance in genotyped hypertrophic cardiomyopathy with normal phenotype.
19087273
2008
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Shared genetic causes of cardiac hypertrophy in children and adults.
18403758
2008
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
CLINVAR
Sarcomeric hypertrophic cardiomyopathy: genetic profile in a Portuguese population.
22857948
2012
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Sudden death due to troponin T mutations.
9060892
1997
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.
22517884
2012
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
The chromosome, its anatomy, and its aberrations.
2003160
1991
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Exome Sequencing Identifies Pathogenic and Modifier Mutations in a Child With Sporadic Dilated Cardiomyopathy.
26656454
2015
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Whole exome sequencing identifies a troponin T mutation hot spot in familial dilated cardiomyopathy.
24205113
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.
8205619
1994
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model.
23383212
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Clinical manifestations of hypertrophic cardiomyopathy with mutations in the cardiac beta-myosin heavy chain gene or cardiac troponin T gene.
8951566
1996
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins.
20079745
2010
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy.
10617660
2000
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Molecular effects of familial hypertrophic cardiomyopathy-related mutations in the TNT1 domain of cTnT.
22579624
2012
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Dilated cardiomyopathy caused by a novel TNNT2 mutation-added value of genetic testing in the correct identification of affected subjects.
19324435
2010