×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy.
11034944
2000
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
CLINVAR
Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy.
11034944
2000
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Characterization of the two eIF4A-binding sites on human eIF4G-1.
11060291
2001
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy.
11106718
2000
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Inotropic stimulation induces cardiac dysfunction in transgenic mice expressing a troponin T (I79N) mutation linked to familial hypertrophic cardiomyopathy.
11113119
2001
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T.
11158969
2001
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region.
11606294
2001
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Novel cardiac troponin T mutation as a cause of familial dilated cardiomyopathy.
11684629
2001
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.
11773635
2002
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy.
12186860
2002
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
CLINVAR
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy.
12707239
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
UNIPROT
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy.
12707239
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy.
12707239
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
CLINVAR
Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy.
12860912
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Different functional properties of troponin T mutants that cause dilated cardiomyopathy.
12923187
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy.
12974739
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
UNIPROT
Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy.
12974739
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Prevalence and clinical profile of troponin T mutations among patients with hypertrophic cardiomyopathy in tuscany.
14636924
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
14654368
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction.
14722098
2004
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy.
15542288
2004
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Mutations profile in Chinese patients with hypertrophic cardiomyopathy.
15563892
2005
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
UNIPROT
Mutations profile in Chinese patients with hypertrophic cardiomyopathy.
15563892
2005
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform.
15623536
2005
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Mutation screening in dilated cardiomyopathy: prominent role of the beta myosin heavy chain gene.
15769782
2005