Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 Biomarker disease CTD_human
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families. 21537932 2011
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene. 27913932 2017
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. 21990120 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. 21990120 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease UNIPROT Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population. 26261251 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Deleterious RAD51C germline mutations rarely predispose to breast and ovarian cancer in Pakistan. 24800917 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Deleterious RAD51C germline mutations rarely predispose to breast and ovarian cancer in Pakistan. 24800917 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer. 28905878 2017
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 Biomarker disease CLINGEN Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 Biomarker disease GENOMICS_ENGLAND Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Enhanced non-homologous end joining contributes toward synthetic lethality of pathological RAD51C mutants with poly (ADP-ribose) polymerase. 25292178 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 Biomarker disease GENOMICS_ENGLAND Exome sequencing reveals a novel Fanconi group defined by XRCC2 mutation. 22232082 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility. 21750962 2011
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075 2017
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550 2013
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 CausalMutation disease CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550 2013
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		0.710 GeneticVariation disease CLINVAR Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. 20400964 2010