Disease: Pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
DUOX1 Q9NRD9 dual oxidase 1 Enzyme 6.2E-33 0.570 0.692
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
DUOX2 Q9NRD8 dual oxidase 2 Enzyme 4.5E-56 0.533 0.769
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
MIR223 microRNA 223 0.433 0.808
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FGF7 P21781 fibroblast growth factor 7 Signaling 0.77 0.519 0.846
TNC P24821 tenascin C 1.3E-07 0.433 0.846
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
MFAP1 P55081 microfibril associated protein 1 Extracellular structure 0.80 0.431 0.846
PRKAA1 Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 0.14 0.453 0.846
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846
PRKAB1 Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 5.3E-03 0.460 0.846
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
TBPL1 P62380 TATA-box binding protein like 1 Transcription factor 0.38 0.506 0.846
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846