Disease: Pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR143 microRNA 143 0.462 0.885
MIR21 microRNA 21 0.363 0.846
MIR223 microRNA 223 0.433 0.808
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885