Disease: Pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
MIR143 microRNA 143 0.462 0.885
MIR21 microRNA 21 0.363 0.846
MIR223 microRNA 223 0.433 0.808
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
DUOX2 Q9NRD8 dual oxidase 2 Enzyme 4.5E-56 0.533 0.769
DUOX1 Q9NRD9 dual oxidase 1 Enzyme 6.2E-33 0.570 0.692
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TNC P24821 tenascin C 1.3E-07 0.433 0.846
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769