Disease: Substance Use Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACKR3 P25106 atypical chemokine receptor 3 G-protein coupled receptor 0.39 0.428 0.885
ADRA1A P35348 adrenoceptor alpha 1A G-protein coupled receptor 3.4E-07 0.462 0.846
ADRA2B P18089 adrenoceptor alpha 2B G-protein coupled receptor 4.5E-06 0.465 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRS3 P32247 bombesin receptor subtype 3 G-protein coupled receptor 0.95 0.474 0.846
CALM1 P0DP23 P0DP24 P0DP25 calmodulin 1 Calcium-binding protein 0.94 0.472 0.808
CALM2 P0DP23 P0DP24 P0DP25 calmodulin 2 Calcium-binding protein 0.92 0.472 0.808
CALM3 P0DP23 P0DP24 P0DP25 calmodulin 3 Calcium-binding protein 0.93 0.485 0.846
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CXCR6 O00574 C-X-C motif chemokine receptor 6 G-protein coupled receptor 5.7E-05 0.448 0.885
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
GPR42 O15529 G protein-coupled receptor 42 (gene/pseudogene) G-protein coupled receptor 5.1E-02 0.475 0.846
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846