Disease: Familial Alzheimer Disease (FAD)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
CLU P10909 clusterin 7.8E-05 0.426 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808