Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731
DSG1 Q02413 desmoglein 1 Cell adhesion 0.93 0.606 0.538
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808
EVPL Q92817 envoplakin Cellular structure 5.7E-25 0.599 0.423
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808
KLKB1 P03952 kallikrein B1 Enzyme 6.3E-13 0.604 0.692
KRT1 P04264 keratin 1 0.74 0.575 0.654
KRT10 P13645 keratin 10 2.5E-03 0.579 0.692
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731