|
rs13181
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Univariate statistical analyses revealed that patients with <i>ERCC2</i> rs13181 T/G and/or <i>CYP3A4</i> rs2740574 A/G genotypes are more likely to develop alopecia; patients with <i>ERCC2</i> rs238406 C/C genotype may develop leukopenia, and patients with <i>GSTT1</i>-null genotype could develop lymphocytopenia (III-IV).
|
30914949 |
2019 |
|
rs1878327
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CGCG haplotype was significantly more common in SLE than in HSs. rs4945 was associated with the erythrocyte sedimentation rate and rs1878327 was associated with alopecia, C-reactive protein, complement 3, anti-dsDNA antibody, and high disease activity. rs2271715 and rs3743388 were associated with renal disease, cumulative glucocorticoid dose, and cyclophosphamide and mycophenolate mofetil use.
|
31811237 |
2019 |
|
rs238406
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Univariate statistical analyses revealed that patients with <i>ERCC2</i> rs13181 T/G and/or <i>CYP3A4</i> rs2740574 A/G genotypes are more likely to develop alopecia; patients with <i>ERCC2</i> rs238406 C/C genotype may develop leukopenia, and patients with <i>GSTT1</i>-null genotype could develop lymphocytopenia (III-IV).
|
30914949 |
2019 |
|
rs2740574
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Univariate statistical analyses revealed that patients with <i>ERCC2</i> rs13181 T/G and/or <i>CYP3A4</i> rs2740574 A/G genotypes are more likely to develop alopecia; patients with <i>ERCC2</i> rs238406 C/C genotype may develop leukopenia, and patients with <i>GSTT1</i>-null genotype could develop lymphocytopenia (III-IV).
|
30914949 |
2019 |
|
rs3743388
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CGCG haplotype was significantly more common in SLE than in HSs. rs4945 was associated with the erythrocyte sedimentation rate and rs1878327 was associated with alopecia, C-reactive protein, complement 3, anti-dsDNA antibody, and high disease activity. rs2271715 and rs3743388 were associated with renal disease, cumulative glucocorticoid dose, and cyclophosphamide and mycophenolate mofetil use.
|
31811237 |
2019 |
|
rs4945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CGCG haplotype was significantly more common in SLE than in HSs. rs4945 was associated with the erythrocyte sedimentation rate and rs1878327 was associated with alopecia, C-reactive protein, complement 3, anti-dsDNA antibody, and high disease activity. rs2271715 and rs3743388 were associated with renal disease, cumulative glucocorticoid dose, and cyclophosphamide and mycophenolate mofetil use.
|
31811237 |
2019 |
|
rs755622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Macrophage migration inhibitory factor polymorphism (rs755622) in alopecia areata: a possible role in disease prevention.
|
31154458 |
2019 |
|
rs187238
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1946518 (-607C>A) and rs187238 (-137G>C) polymorphisms were found associated with alopecia areata disease.
|
29349811 |
2018 |
|
rs1946518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1946518 (-607C>A) and rs187238 (-137G>C) polymorphisms were found associated with alopecia areata disease.
|
29349811 |
2018 |
|
rs116548533
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Without affecting the expression, conformation, nuclear location of VDR or heteridimerization with RXR, VDR-R343H impairs the transactivation activity of VDR on downstream transcription, accounting for HVDRR features with alopecia.
|
29127362 |
2017 |
|
rs121909800
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Alopecia was seen only with the p.R391S mutation.
|
28301319 |
2017 |
|
rs201249971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Homozygotes for the LIPH c.736T>A (p.C246S) mutation, the most prevalent genotype in Japanese patients, present varying degrees of hair loss; however, determinants of this phenotypic diversity remain elusive.
|
27375176 |
2017 |
|
rs377423996
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Without affecting the expression, conformation, nuclear location of VDR or heteridimerization with RXR, VDR-R343H impairs the transactivation activity of VDR on downstream transcription, accounting for HVDRR features with alopecia.
|
29127362 |
2017 |
|
rs778638622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two different homozygous mutations in the VDR gene were identified in 6 patients: the p.K45E mutation located in the DNA-binding domain (5 patients with alopecia) and a novel p.T415R mutation located in the ligand-binding domain.
|
28013309 |
2017 |
|
rs191806896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Sequence analysis identified a novel homozygous missense variant [c.1493C > T (p.Pro498Leu)] in the DSP gene as the underlying genetic cause of non-syndromic alopecia in the family.
|
26148547 |
2015 |
|
rs761051181
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Sequence analysis identified a novel homozygous missense variant [c.1493C > T (p.Pro498Leu)] in the DSP gene as the underlying genetic cause of non-syndromic alopecia in the family.
|
26148547 |
2015 |
|
rs141480813
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report a unique patient, a 14 year old male from Lazio region, affected by common variable immunodeficiency associated with autoimmune manifestations (alopecia, onychodystrophy) and heterozygote for the S250C variant located in the SAND domain of the autoimmune regulator gene protein.
|
25068407 |
2014 |
|
rs201868115
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The severe phenotype of complete baldness was seen in only 1 patient with homozygous c.742C>A.
|
24586639 |
2014 |
|
rs2294020
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that rs2294020 SNP of FOXP3 gene and rs378299 SNP of ICOSLG gene are associated with AA and with a reduced expression of the FOXP3 and ICOSLG genes in alopecia patients.
|
23196741 |
2014 |
|
rs3138869
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We aimed to compare the rs4045402 and rs3138869 polymorphisms prevalence in a group of 69 selected subjects (AGA+PFS) that used finasteride to treat alopecia and developed persistent side effects, with that in a group of 91 untreated subjects with AGA (AGA), and a group of 76 untreated subjects without AGA (NO-AGA).
|
24855036 |
2014 |
|
rs378299
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that rs2294020 SNP of FOXP3 gene and rs378299 SNP of ICOSLG gene are associated with AA and with a reduced expression of the FOXP3 and ICOSLG genes in alopecia patients.
|
23196741 |
2014 |
|
rs6457452
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of HSPA1B SNP rs6457452 with Alopecia Areata in the Korean population.
|
24303776 |
2014 |
|
rs3820706
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified an SNP significantly associated with drug-induced grade 2 alopecia (rs3820706 in CACNB4 (calcium channel voltage-dependent subunit beta 4) on 2q23, P = 8.13 × 10(-9), OR = 3.71) and detected several SNPs that showed some suggestive associations by subgroup analyses.
|
24025145 |
2013 |
|
rs1057517491
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cx26-G45E mice displayed reduced viability, hyperkeratosis, scaling, skin folds, and hair loss.
|
22031297 |
2011 |
|
rs267607477
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The sequence analysis revealed a splice acceptor site mutation (c.IVS8-1G>A) in family A and a missense variant (c.1444G>A, p.Asp482Asn) in family B. Mutations identified in the present study extend the body of evidence implicating the KRT74 gene in the pathogenesis of autosomal dominant hair loss disorders.
|
21188418 |
2011 |