Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121434500
rs121434500
SNTA1
A 0.700 GeneticVariation CLINVAR

dbSNP: rs199473260
rs199473260
SCN5A
C 0.700 GeneticVariation CLINVAR

dbSNP: rs7164883
rs7164883
HCN4
0.820 GeneticVariation BEFREE <b>Conclusion:</b><i>HCN4</i> rs498005 and rs7164883 polymorphisms are significantly associated with AF risk. 31315459

2019
dbSNP: rs498005
rs498005
HCN4
0.010 GeneticVariation BEFREE <b>Conclusion:</b><i>HCN4</i> rs4980</span>05 and rs7164883 polymorphisms are significantly associated with AF risk. 31315459

2019
dbSNP: rs147750704
rs147750704
KCNJ2
0.020 GeneticVariation BEFREE The aim of this simulation study was to identify at cell and tissue levels' mechanisms by which increased I(K1) facilitates and perpetuates AF.The Courtemanche et al. human atrial cell action potential (AP) model was modified to incorporate reported changes in I(K1) induced by the Kir2.1 V93I mutation in both heterozygous (Het) and homozygous (Hom) mutant forms. 19041665

2009
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.010 GeneticVariation BEFREE C825T polymorphism of the G-protein beta3 subunit gene and atrial fibrillation: association of the TT genotype with a reduced risk for atrial fibrillation. 15389246

2004
dbSNP: rs1805127
rs1805127
KCNE1
0.100 GeneticVariation BEFREE G38S polymorphism in the MinK gene could be used as a genetic marker of risk of lone AF. 17165161

2006
dbSNP: rs199473457
rs199473457
KCNQ1
0.010 GeneticVariation BEFREE R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation. 20850564

2011
dbSNP: rs956828658
rs956828658
KCNH2
0.010 GeneticVariation BEFREE R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation. 20850564

2011
dbSNP: rs58238559
rs58238559
ABCB4
0.010 GeneticVariation BEFREE rs58238559 in ABCB4 is a rare missense variant with a significant effect on the development of AFL/AF. 25888430

2015
dbSNP: rs2890565
rs2890565
UTS2
0.010 GeneticVariation BEFREE Ser89Asn polymorphisms of the UTS2 gene are significantly associated with atrial fibrillation in the Chinese population. 26811505

2016
dbSNP: rs2200733
rs2200733 		0.900 GeneticVariation BEFREE rs2200733 risk allele at the 4q25 predicted impaired clinical response to catheter ablation for AF in Chinese Han population. 27843048

2017
dbSNP: rs768138092
rs768138092
SHOX2 ; RSRC1
0.010 GeneticVariation BEFREE A heterozygous missense mutation (p.P33R) was identified in the SND cohort and four heterozygous variants (p.G77D, p.L129=, p.L130F, p.A293=) in the AF cohort. 31354791

2019
dbSNP: rs1291725984
rs1291725984
SHOX2
0.010 GeneticVariation BEFREE A heterozygous missense mutation (p.P33R) was identified in the SND cohort and four heterozygous variants (p.G77D, p.L129=, p.L130F, p.A293=) in the AF cohort. 31354791

2019
dbSNP: rs1799983
rs1799983
NOS3
0.010 GeneticVariation BEFREE A multiple logistic regression analysis showed that presence of the rs1799983 variant (OR 1.75, 95% CI 1.07-2.86, p=0.026) and persistent AF were independent predictors for ERAF after AF ablation. 26256966

2015
dbSNP: rs28933093
rs28933093
LMNA
0.010 GeneticVariation BEFREE A new missense (E161K) mutation was identified in a family with early atrial fibrillation and a previously described (R377H) mutation in another family with a quadriceps myopathy associated with DCM. 12920062

2003
dbSNP: rs61672878
rs61672878
LMNA
0.010 GeneticVariation BEFREE A new missense (E161K) mutation was identified in a family with early atrial fibrillation and a previously described (R377H) mutation in another family with a quadriceps myopathy associated with DCM. 12920062

2003
dbSNP: rs587777556
rs587777556
SCN3B
0.010 GeneticVariation BEFREE A novel A130V mutation was identified in a 46-year-old patient with lone AF, and the mutation was absent in 500 controls. 20558140

2010
dbSNP: rs199472708
rs199472708
KCNQ1
0.030 GeneticVariation BEFREE A novel KCNQ1-G229D mutation identified in a juvenile-onset AF patient altered the IKs activity and kinetics, thereby increasing the arrhythmogenicity to AF. 24096004

2014
dbSNP: rs199472952
rs199472952
KCNH2
0.010 GeneticVariation BEFREE A novel KCNQ1-G229D mutation identified in a juvenile-onset AF patient altered the IKs activity and kinetics, thereby increasing the arrhythmogenicity to AF. 24096004

2014
dbSNP: rs781255319
rs781255319
KCNH2
0.010 GeneticVariation BEFREE A novel KCNQ1-G229D mutation identified in a juvenile-onset AF patient altered the IKs activity and kinetics, thereby increasing the arrhythmogenicity to AF. 24096004

2014
dbSNP: rs199473324
rs199473324
SCN5A
0.010 GeneticVariation BEFREE A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation. 18929244

2008
dbSNP: rs2200733
rs2200733 		0.900 GeneticVariation GWASCAT A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. 19597491

2009
dbSNP: rs2200733
rs2200733 		0.900 GeneticVariation GWASDB A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. 19597491

2009
dbSNP: rs2220427
rs2220427 		0.800 GeneticVariation GWASDB A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. 19597491

2009