Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121434500
rs121434500
SNTA1
A 0.700 GeneticVariation CLINVAR

dbSNP: rs199473260
rs199473260
SCN5A
C 0.700 GeneticVariation CLINVAR

dbSNP: rs121908990
rs121908990
PRKAG2
0.010 GeneticVariation BEFREE We identified a novel mutation (Arg531Gly) in the gamma-2 regulatory subunit (PRKAG2) of AMP-activated protein kinase (AMPK) to be responsible for a syndrome associated with ventricular preexcitation and early onset of atrial fibrillation and conduction disease. 11748095

2001
dbSNP: rs120074192
rs120074192
KCNQ1
0.050 GeneticVariation BEFREE Thus, the S140G mutation is likely to initiate and maintain AF by reducing action potential duration and effective refractory period in atrial myocytes. 12522251

2003
dbSNP: rs28933093
rs28933093
LMNA
0.010 GeneticVariation BEFREE A new missense (E161K) mutation was identified in a family with early atrial fibrillation and a previously described (R377H) mutation in another family with a quadriceps myopathy associated with DCM. 12920062

2003
dbSNP: rs61672878
rs61672878
LMNA
0.010 GeneticVariation BEFREE A new missense (E161K) mutation was identified in a family with early atrial fibrillation and a previously described (R377H) mutation in another family with a quadriceps myopathy associated with DCM. 12920062

2003
dbSNP: rs699
rs699
AGT
0.050 GeneticVariation BEFREE In single-locus analysis, M235T, G-6A, and G-217A were significantly associated with AF. 15023884

2004
dbSNP: rs1267969615
rs1267969615
ACE
0.030 GeneticVariation BEFREE In single-locus analysis, M235T, G-6A, and G-217A were significantly associated with AF. 15023884

2004
dbSNP: rs62492438
rs62492438
KCNH2
0.010 GeneticVariation BEFREE Thus, KCNE2 R27C is a gain-of-function mutation associated with the initiation and/or maintenance of AF. 15368194

2004
dbSNP: rs74315449
rs74315449
KCNE2 ; LOC105372791
0.010 GeneticVariation BEFREE Thus, KCNE2 R27C is a gain-of-function mutation associated with the initiation and/or maintenance of AF. 15368194

2004
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.010 GeneticVariation BEFREE C825T polymorphism of the G-protein beta3 subunit gene and atrial fibrillation: association of the TT genotype with a reduced risk for atrial fibrillation. 15389246

2004
dbSNP: rs147750704
rs147750704
KCNJ2
0.020 GeneticVariation BEFREE Kir2.1 V93I mutation may play a role in initiating and/or maintaining AF by increasing the activity of the inward rectifier K(+) channel. 15922306

2005
dbSNP: rs1805127
rs1805127
KCNE1
0.100 GeneticVariation BEFREE The minor allele frequencies of P448R, R519H, G643S for KCNQ1 and G38S and D85N for KCNE1 in the AF group, the community control group and the ward control group were 9.9, 7.9, 9.3%; 0, 0, -; 4.3, 4.2, 1.7%; 28.4, 31.7, 29.7%; 0.7, 0.4%, -, respectively. 17016049

2007
dbSNP: rs1805128
rs1805128
KCNE1
0.010 GeneticVariation BEFREE The minor allele frequencies of P448R, R519H, G643S for KCNQ1 and G38S and D85N for KCNE1 in the AF group, the community control group and the ward control group were 9.9, 7.9, 9.3%; 0, 0, -; 4.3, 4.2, 1.7%; 28.4, 31.7, 29.7%; 0.7, 0.4%, -, respectively. 17016049

2007
dbSNP: rs1805127
rs1805127
KCNE1
0.100 GeneticVariation BEFREE G38S polymorphism in the MinK gene could be used as a genetic marker of risk of lone AF. 17165161

2006
dbSNP: rs199473444
rs199473444
KCNQ1
0.010 GeneticVariation BEFREE These data suggest that the R14C KCNQ1 mutation alone is insufficient to cause AF. 17276182

2007
dbSNP: rs1217691063
rs1217691063
MTHFR
0.010 GeneticVariation BEFREE Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility. 17551576

2007
dbSNP: rs1805087
rs1805087
MTR
0.010 GeneticVariation BEFREE Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility. 17551576

2007
dbSNP: rs375752214
rs375752214
NOS3
0.010 GeneticVariation BEFREE Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility. 17551576

2007
dbSNP: rs10033464
rs10033464 		T 0.900 GeneticVariation GWASDB Variants conferring risk of atrial fibrillation on chromosome 4q25. 17603472

2007
dbSNP: rs10033464
rs10033464 		T 0.900 GeneticVariation GWASCAT Variants conferring risk of atrial fibrillation on chromosome 4q25. 17603472

2007
dbSNP: rs2200733
rs2200733 		T 0.900 GeneticVariation GWASCAT Variants conferring risk of atrial fibrillation on chromosome 4q25. 17603472

2007
dbSNP: rs2200733
rs2200733 		T 0.900 GeneticVariation GWASDB Variants conferring risk of atrial fibrillation on chromosome 4q25. 17603472

2007
dbSNP: rs2220427
rs2220427 		0.800 GeneticVariation GWASDB Variants conferring risk of atrial fibrillation on chromosome 4q25. 17603472

2007
dbSNP: rs2634073
rs2634073 		0.710 GeneticVariation GWASDB Variants conferring risk of atrial fibrillation on chromosome 4q25. 17603472

2007