rs62619935
|
|
T |
0.710 |
CausalMutation |
CLINVAR |
|
|
|
rs121913224
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs121913327
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs137854573
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs137854575
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1400295986
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs145945630
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1554085355
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs397515734
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs587781392
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs779998847
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
rs786201856
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs863225311
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs876660765
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1801155
|
|
A |
0.800 |
SusceptibilityMutation |
CLINVAR |
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.
|
9288102 |
1997 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The I1307K APC mutation does not predispose to colorectal cancer in Jewish Ashkenazi breast and breast-ovarian cancer kindreds.
|
9407954 |
1997 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The I1307K APC mutation does not predispose to colorectal cancer in Jewish Ashkenazi breast and breast-ovarian cancer kindreds.
|
9407954 |
1997 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Among the 1087 first-degree relatives, there were 23 cases of colorectal cancer; 3 of 100 relatives of probands with the I1307K allele (3.0%) had a history of colorectal cancer versus 20 of 987 relatives of probands without the I1307K allele (2.1%; relative risk, 1.48; 95% confidence interval, 0.45-4.88; P = 0.462).
|
9679945 |
1998 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Among the 1087 first-degree relatives, there were 23 cases of colorectal cancer; 3 of 100 relatives of probands with the I1307K allele (3.0%) had a history of colorectal cancer versus 20 of 987 relatives of probands without the I1307K allele (2.1%; relative risk, 1.48; 95% confidence interval, 0.45-4.88; P = 0.462).
|
9679945 |
1998 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Our data show that the I1307K variant is rare in the Norwegian population and should not be viewed as a candidate for susceptibility testing for colorectal cancer.
|
9679946 |
1998 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our data show that the I1307K variant is rare in the Norwegian population and should not be viewed as a candidate for susceptibility testing for colorectal cancer.
|
9679946 |
1998 |
rs1801155
|
|
A |
0.800 |
SusceptibilityMutation |
CLINVAR |
The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
|
9724771 |
1998 |
rs1801155
|
|
A |
0.800 |
SusceptibilityMutation |
CLINVAR |
The I1307K allele was found in 6.1% of unselected Ashkenazi Jews and higher proportions of Ashkenazim with family or personal histories of CRC (ref.2).
|
9731533 |
1998 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The I1307K allele was found in 6.1% of unselected Ashkenazi Jews and higher proportions of Ashkenazim with family or personal histories of CRC (ref.2).
|
9731533 |
1998 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The I1307K allele was found in 6.1% of unselected Ashkenazi Jews and higher proportions of Ashkenazim with family or personal histories of CRC (ref.2).
|
9731533 |
1998 |