rs1799983
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0.100 |
GeneticVariation |
BEFREE |
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characterized as a risk factor of hypertension and coronary artery disease.
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21816783 |
2011 |
rs1799983
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|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, the protective HO1 promoter polymorphism correlates with a lower coronary artery plaque burden, whereas the protective ENOS 894 G/T polymorphism seems to favourably influence changes of coronary artery plaque composition during statin therapy, but has no significant correlation to the magnitude of coronary atherosclerosis.
|
22123460 |
2011 |
rs1799983
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0.100 |
GeneticVariation |
BEFREE |
Association of endothelial dysfunction with endothelin, nitric oxide and eNOS Glu298Asp gene polymorphism in coronary artery disease.
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22045428 |
2011 |
rs662
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0.100 |
GeneticVariation |
BEFREE |
We tested the clinical relevance of the PON1 Q192R genotype in a population of individuals with coronary artery disease who underwent stent implantation and received clopidogrel therapy.
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21170047 |
2011 |
rs662
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0.100 |
GeneticVariation |
BEFREE |
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
|
21982484 |
2011 |
rs1217691063
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|
|
0.100 |
GeneticVariation |
BEFREE |
The C677T polymorphism of 5,10 methylenetetrahydrofolate reductase (MTHFR) gene has been associated with hypertension and coronary artery disease in several populations worldwide, but results are still controversial.
|
20637366 |
2010 |
rs1799983
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0.100 |
GeneticVariation |
BEFREE |
G894T polymorphism of eNOS gene was not associated with foot ulcer and diabetic complications, except in the presence of atherosclerotic heart disease.
|
20642368 |
2010 |
rs1799983
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0.100 |
GeneticVariation |
BEFREE |
This study, for the first time, suggests an independent association of 894G>T and -786T>C polymorphisms of endothelial nitric oxide synthase gene with coronary artery disease in a Saudi population.
|
20470943 |
2010 |
rs1799983
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0.100 |
GeneticVariation |
BEFREE |
The G894T polymorphism in the eNOS gene might influence coronary atherosclerosis rather than ICAS in Koreans.
|
21114134 |
2010 |
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been associated with hypertension and coronary artery disease in several populations worldwide, but results are still controversial.
|
20083095 |
2010 |
rs1799983
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|
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0.100 |
GeneticVariation |
BEFREE |
Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial nitric oxide synthase gene in patients with coronary artery disease.
|
19434512 |
2010 |
rs662
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0.100 |
GeneticVariation |
BEFREE |
A preliminary study of human paraoxonase and PON 1 L/M55-PON 1 Q/R 192 polymorphisms in Turkish patients with coronary artery disease.
|
19226538 |
2009 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes.
|
18586656 |
2008 |
rs1217691063
|
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|
0.100 |
GeneticVariation |
BEFREE |
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with early onset of coronary artery disease in some populations with certain ethnic backgrounds.
|
18751630 |
2008 |
rs1217691063
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|
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0.100 |
GeneticVariation |
BEFREE |
Plasma homocysteine levels & 677C-->T methylenetetrahydrofolate reductase gene polymorphism in patients with coronary artery disease of different severity.
|
18403793 |
2008 |
rs699
|
|
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0.100 |
GeneticVariation |
BEFREE |
The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia.
|
18409009 |
2008 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
Dynamic regulation of MTHFR mRNA expression and C677T genotype modulate mortality in coronary artery disease patients after revascularization.
|
17604826 |
2007 |
rs1217691063
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|
|
0.100 |
GeneticVariation |
BEFREE |
Sex-specific effect of the thermolabile C677T mutation in the methylenetetrahydrofolate reductase gene on angiographically assessed coronary artery disease in Brazilians.
|
18075008 |
2007 |
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The eNOS -786T>C (odds ratio [OR]; 1.61, 95% confidence interval [CI]; 0.97-2.69), 894G>T (OR; 1.12, 95% CI; 0.65-1.92) and 4a4b (OR; 1.44, 95% CI; 0.87-2.39) polymorphisms were not an independent predisposition factor to coronary artery disease.
|
16842840 |
2007 |
rs1217691063
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|
|
0.100 |
GeneticVariation |
BEFREE |
Gene--nutrition interactions in coronary artery disease: correlation between the MTHFR C677T polymorphism and folate and homocysteine status in a Korean population.
|
15935452 |
2006 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.
|
15648053 |
2006 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent studies have shown that a common mutation (nucleotide 677 C-->T) in the methylenetetrahydrofolate reductase (MTHFR) gene may contribute to a mild rise in plasma homocysteine levels and increase the incidence of coronary artery disease.
|
16489563 |
2006 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The oxidative modification of low-density lipoprotein (LDL) has been suggested to be a key element in atherogenesis, while methylenetetrahydrofolate reductase (MTHFR) C677T mutation has been associated with the development of coronary heart disease.
|
16487909 |
2006 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The objective of our study is to evaluate the single locus and combined effects of three different genetic polymorphisms (methylenetetrahydrofolate reductase C677T polymorphism, plasminogen activator inhibitor 4G/5G polymorphism, and endothelial nitric oxide synthase 3-27 base pairs repeat polymorphism) on the presence and extent of coronary artery disease in patients with early-onset coronary artery disease.
|
16845248 |
2006 |
rs1799983
|
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|
0.100 |
GeneticVariation |
BEFREE |
In Caucasians, association between E298D genotype and risk of coronary heart disease was significantly modified by current smoking status (interaction P=0.013), with the highest risk observed in smokers carrying the variant D298 allele relative to nonsmokers carrying two E298 alleles (adjusted hazard rate ratio 2.07, 95% confidence interval 1.39-3.07).
|
17108813 |
2006 |