|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer.
|
16393309 |
2006 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There were significant associations of the Pro12Ala single nucleotide polymorphism (SNP) genotypes with diabetes in both case-control comparisons (P=0.025 and P=0.039).
|
16401314 |
2005 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There were significant associations of the Pro12Ala single nucleotide polymorphism (SNP) genotypes with diabetes in both case-control comparisons (P=0.025 and P=0.039).
|
16401314 |
2005 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are suggested.
|
16567542 |
2006 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Cumulative rather than synergistic effects of PPARG Pro12Ala and APM1 SNPs on diabetes risk are suggested.
|
16567542 |
2006 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Pro12Ala polymorphism of PPAR-gamma 2 is associated with decreased risk of diabetes mellitus.
|
16881538 |
2006 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Pro12Ala polymorphism of PPAR-gamma 2 is associated with decreased risk of diabetes mellitus.
|
16881538 |
2006 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been associated with decreased risk of diabetes and obesity, both disorders linked to cognitive impairment.
|
17052804 |
2008 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) has been associated with decreased risk of diabetes and obesity, both disorders linked to cognitive impairment.
|
17052804 |
2008 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Across all studies, the Pro12Ala polymorphism had no significant effect on diabetes-related traits.
|
17065690 |
2006 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Across all studies, the Pro12Ala polymorphism had no significant effect on diabetes-related traits.
|
17065690 |
2006 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The proline allele at PPARG P12A increases risk for diabetes in persons with impaired glucose tolerance, an effect modified by body mass index.
|
17213274 |
2007 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The proline allele at PPARG P12A increases risk for diabetes in persons with impaired glucose tolerance, an effect modified by body mass index.
|
17213274 |
2007 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Adiponectin values did not differ among these two genotypes even when categorized based on their diabetes status (normal glucose tolerance Pro12Pro 7.9 vs. Pro12Ala 7.7 microg/ml, P = 0.994; diabetes Pro12Pro 4.7 vs. Pro12Ala 5.4 microg/ml, P = 0.622).
|
17335469 |
2007 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Adiponectin values did not differ among these two genotypes even when categorized based on their diabetes status (normal glucose tolerance Pro12Pro 7.9 vs. Pro12Ala 7.7 microg/ml, P = 0.994; diabetes Pro12Pro 4.7 vs. Pro12Ala 5.4 microg/ml, P = 0.622).
|
17335469 |
2007 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes and systolic blood pressure as the major risk factors for diabetic nephropathy in the Oji-Cree population.
|
17493550 |
2007 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The genetic influence of PPARG P12A genotype is modest and is overshadowed by duration of diabetes and systolic blood pressure as the major risk factors for diabetic nephropathy in the Oji-Cree population.
|
17493550 |
2007 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There appears to be certain genes which predispose Indians to diabetes while other genes (for example Pro 12 Ala polymorphism of PPAR gamma gene) which afford protection against diabetes and insulin resistance to Caucasians, do not appear to protect Indians.
|
17496355 |
2007 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
There appears to be certain genes which predispose Indians to diabetes while other genes (for example Pro 12 Ala polymorphism of PPAR gamma gene) which afford protection against diabetes and insulin resistance to Caucasians, do not appear to protect Indians.
|
17496355 |
2007 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabetes risk.
|
17563457 |
2007 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The role of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma in diabetes risk.
|
17563457 |
2007 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer.
|
17763950 |
2008 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer.
|
17763950 |
2008 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We tested the effect-modifying role of Pro12Ala on the 1 year change in obesity-related traits in a randomised clinical trial of treatment with metformin (n = 989), troglitazone (n = 363) or lifestyle modification (n = 1,004) vs placebo (n = 1,000) for diabetes prevention in high-risk individuals.
|
17898990 |
2007 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We tested the effect-modifying role of Pro12Ala on the 1 year change in obesity-related traits in a randomised clinical trial of treatment with metformin (n = 989), troglitazone (n = 363) or lifestyle modification (n = 1,004) vs placebo (n = 1,000) for diabetes prevention in high-risk individuals.
|
17898990 |
2007 |