|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Heart failure and endothelial nitric oxide synthase G894T gene polymorphism frequency variations within ancestries.
|
28554876 |
2018 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
To evaluate the association between G894T GP and the prognosis of a sample of Brazilian outpatients with heart failure.
|
23949326 |
2013 |
|
rs1801252
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Data from our study suggest that the β adrenoreceptor Gly 49 allele of the β1 -adrenergic receptor Ser(49) Gly polymorphisms may increase the risk of ICD shock in patients with heart failure, independent of beta-blocker dosage.
|
27027728 |
2016 |
|
rs1801252
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) within the β(1)- (Ser49Gly, Arg389Gly) and β(2)-adrenoceptor (Arg16Gly, Gln27Glu, Thr164Ile) have been associated with alterations in adrenoceptor (AR) function sensitivity in vitro and in vivo and possibly contribute to HF progression.
|
20803192 |
2010 |
|
rs1801252
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The Ser49Gly polymorphism did not impact the risk or prognosis of HF.
|
22815685 |
2012 |
|
rs1801252
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The objective of this study was to determine whether ADRB1 Ser49Gly and Arg389Gly are associated with recovery of left ventricular ejection fraction (LVEF) in patients with heart failure.
|
30756358 |
2019 |
|
rs1801252
|
|
|
0.060 |
GeneticVariation |
BEFREE |
These data suggest that the beta(1)-receptor Ser49Gly variant might be associated with altered receptor function, resulting in myocardial protection in patients with heart failure.
|
11052857 |
2000 |
|
rs1801252
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We tested the hypothesis that polymorphisms at codons 389 (Arg389Gly) and 49 (Ser49Gly) of the beta(1)-adrenergic receptor would be associated with differences in initial tolerability of beta-blocker therapy in patients with heart failure.
|
15735607 |
2005 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The DD allele frequency is lower in Chinese, but the M235T variant of the angiotensinogen gene is more common in Chinese than whites; it is not known to what extent polymorphisms of the renin-angiotensin system affect clinical status or prognosis in Chinese patients with heart failure.
|
10097225 |
1999 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Association of two angiotensinogen gene polymorphisms, M235T and G(-6)A, with chronic heart failure.
|
12767551 |
2003 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
To investigate a role of AGT G(-6)A and M235T genetic variants for chronic heart failure (CHF) and advanced atherosclerosis (AA), a total of 240 patients with CHF and 200 patients with AA of the Czech origin were evaluated for the study.
|
20945963 |
2011 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The current meta-analysis suggests that M235T polymorphism might be associated with increased risk of heart failure in Caucasians.
|
23154270 |
2014 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Angiotensinogen M235T and T174M gene polymorphisms in combination doubles the risk of mortality in heart failure.
|
17145981 |
2007 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The pooled data showed that there was no significant associations between the AGT M235T polymorphism and HF</span> risk for TT vs. MM (OR = 1.17, 95%CI = 0.62-2.19, P = 0.635), MT vs. MM (OR = 0.97, 95%CI = 0.77-1.22, P = 0.776), MT/TT vs. MM (OR = 1.07, 95%CI = 0.67-1.69, P = 0.781), and TT vs. MM/MT (OR = 1.23, 95%CI = 0.86-1.76, P = 0.259).
|
24572548 |
2014 |
|
rs1042713
|
|
|
0.040 |
GeneticVariation |
BEFREE |
This Arg16Gly genotype-dependent heterogeneity in clinical outcomes of HF was successfully validated in the second independent population.
|
30374408 |
2018 |
|
rs1042713
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Arginine 16 glycine beta2-adrenoceptor polymorphism and cardiovascular structure and function in patients with heart failure.
|
17336757 |
2007 |
|
rs1042713
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) within the β(1)- (Ser49Gly, Arg389Gly) and β(2)-adrenoceptor (Arg16Gly, Gln27Glu, Thr164Ile) have been associated with alterations in adrenoceptor (AR) function sensitivity in vitro and in vivo and possibly contribute to HF progression.
|
20803192 |
2010 |
|
rs1042713
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Beta-2 adrenergic receptor gene polymorphisms Gln27Glu, Arg16Gly in patients with heart failure.
|
19886995 |
2009 |
|
rs1042714
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We investigated whether a predefined combination of the Arg389Gly polymorphism in the adrenergic β(1) -receptor gene (ADRB1) and the Gln27Glu polymorphism in the adrenergic β(2) -receptor gene (ADRB2) could predict survival in carvedilol- and metoprolol-treated chronic heart failure (HF) patients.
|
21395649 |
2011 |
|
rs1042714
|
|
|
0.040 |
GeneticVariation |
BEFREE |
There was no difference in the prevalence of polymorphism Gln27Glu between HF patients and control subjects.
|
28933308 |
2018 |
|
rs1042714
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We investigated the clinical response of chronic heart failure patients with beta(2)-adrenergic receptor Gln(27)-->Glu polymorphism treated for 6 months with carvedilol, a alpha/beta-antagonist with antioxidant properties.The 6-min. walk test, the left ventricular ejection fraction, heart rate, plasma norepinephrine and malondialdehyde, a stress oxidative marker, concentrations were evaluated at baseline and after treatment for 6 months with carvedilol in 33 stable chronic heart failure patients with the Gln(27)-->Glubeta(2)-adrenergic receptor polymorphism.
|
19422106 |
2009 |
|
rs1042714
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) within the β(1)- (Ser49Gly, Arg389Gly) and β(2)-adrenoceptor (Arg16Gly, Gln27Glu, Thr164Ile) have been associated with alterations in adrenoceptor (AR) function sensitivity in vitro and in vivo and possibly contribute to HF progression.
|
20803192 |
2010 |
|
rs1320702652
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Several studies identified that polymorphism of AMP deaminase 1 gene (AMPD1), in particular the common C34T variant of this gene was found to benefit patients with heart failure and ischemic heart disease.
|
24431031 |
2014 |
|
rs1320702652
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Possession of the C34T (Glu12Stop) nonsense mutation in the AMP-deaminase 1 (AMPD1) gene has been shown to be associated with improved prognosis in heart failure and ischemic heart disease.
|
14499869 |
2003 |
|
rs1320702652
|
|
|
0.040 |
GeneticVariation |
BEFREE |
C34T AMPD1 polymorphism may be associated with reduced frequency of obesity in CAD patients and of hyperglycaemia and diabetes in both CAD and HF patients.
|
18855224 |
2009 |