rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Genotype-phenotype correlation in Costello syndrome: HRAS mutation analysis in 43 cases.
|
16443854 |
2006 |
rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Recurring HRAS mutation G12S in Dutch patients with Costello syndrome.
|
16881968 |
2006 |
rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
HRAS mutations in Costello syndrome: detection of constitutional activating mutations in codon 12 and 13 and loss of wild-type allele in malignancy.
|
16372351 |
2006 |
rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Somatic mosaicism for an HRAS mutation causes Costello syndrome.
|
16969868 |
2006 |
rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
HRAS mutation analysis in Costello syndrome: genotype and phenotype correlation.
|
16329078 |
2006 |
rs1800888
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The prevalence of the hypofunctional Thr164Ile</span>-beta(2)AR variant and the frequency of the Ile164-allele were almost identical in CHF-patients, who had undergone HTX, with those in patients with stable CHF or in healthy controls.
|
16783489 |
2006 |
rs57045855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The D192G mutation was found in a 26-year-old patient with mild DCM and heart failure leading to death within two years after onset of symptoms.
|
16981056 |
2006 |
rs899115126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ET-1 Lys198Asn and ET(A) receptor H323H polymorphisms seem to act synergistically to increase the risk of HF.
|
16582543 |
2006 |
rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Diversity, parental germline origin, and phenotypic spectrum of de novo HRAS missense changes in Costello syndrome.
|
17054105 |
2007 |
rs1801253
|
|
|
0.100 |
GeneticVariation |
BEFREE |
One study of risk for heart failure suggested a synergistic effect of ADRB1 Arg389Gly with the insertion/deletion polymorphism in the alpha2C-adrenergic receptor gene (ADRA2C).
|
17496726 |
2007 |
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Angiotensinogen M235T and T174M gene polymorphisms in combination doubles the risk of mortality in heart failure.
|
17145981 |
2007 |
rs1042713
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Arginine 16 glycine beta2-adrenoceptor polymorphism and cardiovascular structure and function in patients with heart failure.
|
17336757 |
2007 |
rs10501920
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, rs10501920 in CNTN5 was associated with AF (p = 9.4 x 10(-6)) and HF (p = 1.2 x 10(-4)).
|
17903304 |
2007 |
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype distributions of GSTM1 and GSTT1 deletion polymorphisms and C677T variant of MTHFR were examined in a sample of 94 hypertensive patients with congestive heart failure and 207 healthy unrelated Portuguese individuals using PCR techniques.
|
17182005 |
2007 |
rs1222174664
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype distributions of GSTM1 and GSTT1 deletion polymorphisms and C677T variant of MTHFR were examined in a sample of 94 hypertensive patients with congestive heart failure and 207 healthy unrelated Portuguese individuals using PCR techniques.
|
17182005 |
2007 |
rs2549513
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six associations yielded p < 10(-5).The lowest p-values for each CVD trait were as follows: major CVD, rs499818, p = 6.6 x 10(-6); major CHD, rs2549513, p = 9.7 x 10(-6); AF, rs958546, p = 4.8 x 10(-6); HF: rs740363, p = 8.8 x 10(-6).
|
17903304 |
2007 |
rs4762
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study suggested that angiotensinogen gene variants M235T and T174M may provide prognostic information for long-term survival in heart failure patients.
|
17145981 |
2007 |
rs499818
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six associations yielded p < 10(-5).The lowest p-values for each CVD trait were as follows: major CVD, rs499818, p = 6.6 x 10(-6); major CHD, rs2549513, p = 9.7 x 10(-6); AF, rs958546, p = 4.8 x 10(-6); HF: rs740363, p = 8.8 x 10(-6).
|
17903304 |
2007 |
rs740363
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six associations yielded p < 10(-5).The lowest p-values for each CVD trait were as follows: major CVD, rs499818, p = 6.6 x 10(-6); major CHD, rs2549513, p = 9.7 x 10(-6); AF, rs958546, p = 4.8 x 10(-6); HF: rs740363, p = 8.8 x 10(-6).
|
17903304 |
2007 |
rs958546
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six associations yielded p < 10(-5).The lowest p-values for each CVD trait were as follows: major CVD, rs499818, p = 6.6 x 10(-6); major CHD, rs2549513, p = 9.7 x 10(-6); AF, rs958546, p = 4.8 x 10(-6); HF: rs740363, p = 8.8 x 10(-6).
|
17903304 |
2007 |
rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Severe neonatal manifestations of Costello syndrome.
|
18039947 |
2008 |
rs34376731
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings suggest that the human G147D PPI-1 can attenuate responses of cardiomyocytes to beta-adrenergic agonists by decreasing PLN phosphorylation and therefore may contribute to deteriorated function in heart failure.
|
18192322 |
2008 |
rs5370
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Moreover, the frequency of endothelin-1 Lys198Asn polymorphism was investigated with respect to the prevalence of several actual or historical endorgan damages (renal disorder, coronary artery disease, vascular events, vascular damage, and congestive heart failure) in hypertensive patients.
|
18923236 |
2008 |
rs1056892
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The functional CBR3 V244M polymorphism may have an impact on the risk of anthracycline-related CHF among childhood cancer survivors by modulating the intracardiac formation of cardiotoxic anthracycline alcohol metabolites.
|
18457324 |
2008 |
rs104894229
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Male-to-male transmission of Costello syndrome: G12S HRAS germline mutation inherited from a father with somatic mosaicism.
|
19206176 |
2009 |