Gene: SDHB ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 GeneticVariation CLINVAR The phenotype of SDHB germline mutation carriers: a nationwide study. 28490599

2017
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 GeneticVariation CLINVAR Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes. 25683602

2015
dbSNP: rs397516834
rs397516834
SDHB
A 0.700 GeneticVariation CLINVAR Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients. 27279923

2016
dbSNP: rs570278423
rs570278423
SDHB
T 0.700 GeneticVariation CLINVAR Crystal structure of mitochondrial respiratory membrane protein complex II. 15989954

2005
dbSNP: rs570278423
rs570278423
SDHB
T 0.700 GeneticVariation CLINVAR Genetic mutation screening in an italian cohort of nonsyndromic pheochromocytoma/paraganglioma patients. 17102082

2006
dbSNP: rs570278423
rs570278423
SDHB
T 0.700 GeneticVariation CLINVAR Relevance of germline mutation screening in both familial and sporadic head and neck paraganglioma for early diagnosis and clinical management. 20208144

2010
dbSNP: rs570278423
rs570278423
SDHB
T 0.700 GeneticVariation CLINVAR Yeast model for evaluating the pathogenic significance of SDHB, SDHC and SDHD mutations in PHEO-PGL syndrome. 23175444

2013
dbSNP: rs570278423
rs570278423
SDHB
T 0.700 GeneticVariation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs587782243
rs587782243
SDHB
T 0.700 GeneticVariation CLINVAR Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD. 19802898

2010
dbSNP: rs587782243
rs587782243
SDHB
T 0.700 GeneticVariation CLINVAR Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer. 23083876

2012
dbSNP: rs587782604
rs587782604
SDHB
A 0.700 GeneticVariation CLINVAR Usefulness of Somatostatin Receptor Scintigraphy (Tc-[HYNIC, Tyr3]-Octreotide) and 123I-Metaiodobenzylguanidine Scintigraphy in Patients with SDHx Gene-Related Pheochromocytomas and Paragangliomas Detected by Computed Tomography. 25791839

2015
dbSNP: rs587782604
rs587782604
SDHB
A 0.700 GeneticVariation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs587782604
rs587782604
SDHB
T 0.700 GeneticVariation CLINVAR

dbSNP: rs587782604
rs587782604
SDHB
A 0.700 GeneticVariation CLINVAR Role of rapid sequence whole-body MRI screening in SDH-associated hereditary paraganglioma families. 23934599

2014
dbSNP: rs587782604
rs587782604
SDHB
A 0.700 GeneticVariation CLINVAR Germline SDHB mutations are common in patients with apparently sporadic sympathetic paragangliomas. 18382370

2008
dbSNP: rs587782703
rs587782703
SDHB
A 0.700 GeneticVariation CLINVAR

dbSNP: rs587782904
rs587782904
SDHB
T 0.700 GeneticVariation CLINVAR

dbSNP: rs727503415
rs727503415
SDHB
G 0.700 GeneticVariation CLINVAR Relevance of germline mutation screening in both familial and sporadic head and neck paraganglioma for early diagnosis and clinical management. 20208144

2010
dbSNP: rs727503415
rs727503415
SDHB
G 0.700 GeneticVariation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs727503415
rs727503415
SDHB
G 0.700 GeneticVariation CLINVAR High frequency of germline succinate dehydrogenase mutations in sporadic cervical paragangliomas in northern Spain: mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations. 17848412

2007
dbSNP: rs727503415
rs727503415
SDHB
G 0.700 GeneticVariation CLINVAR Structural basis for malfunction in complex II. 22904323

2012
dbSNP: rs74315367
rs74315367
SDHB
C 0.700 GeneticVariation CLINVAR Functional consequences of a SDHB gene mutation in an apparently sporadic pheochromocytoma. 12364472

2002
dbSNP: rs74315367
rs74315367
SDHB
C 0.700 GeneticVariation CLINVAR Familial paraganglioma: a novel presentation of a case and response to therapy with radiolabelled MIBG. 16982587

2007
dbSNP: rs74315367
rs74315367
SDHB
C 0.700 GeneticVariation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs74315367
rs74315367
SDHB
C 0.700 GeneticVariation CLINVAR An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis. 19576851

2009