Gene: SDHB ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 GeneticVariation CLINVAR Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes. 25683602

2015
dbSNP: rs397516833
rs397516833
SDHB
G 0.700 CausalMutation CLINVAR Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. 25371406

2015
dbSNP: rs397516833
rs397516833
SDHB
G 0.700 CausalMutation CLINVAR Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis. 26302408

2015
dbSNP: rs397516836
rs397516836
SDHB
A 0.700 CausalMutation CLINVAR Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. 25371406

2015
dbSNP: rs587782604
rs587782604
SDHB
A 0.700 GeneticVariation CLINVAR Usefulness of Somatostatin Receptor Scintigraphy (Tc-[HYNIC, Tyr3]-Octreotide) and 123I-Metaiodobenzylguanidine Scintigraphy in Patients with SDHx Gene-Related Pheochromocytomas and Paragangliomas Detected by Computed Tomography. 25791839

2015
dbSNP: rs74315366
rs74315366
SDHB
A 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs74315367
rs74315367
SDHB
C 0.700 GeneticVariation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs74315368
rs74315368
SDHB
T 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs74315368
rs74315368
SDHB
T 0.700 CausalMutation CLINVAR Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma. 25873086

2015
dbSNP: rs74315368
rs74315368
SDHB
T 0.700 CausalMutation CLINVAR Additive effect of nuclear and mitochondrial mutations in a patient with mitochondrial encephalomyopathy. 25736212

2015
dbSNP: rs74315369
rs74315369
SDHB
A 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs74315370
rs74315370
SDHB
A 0.700 CausalMutation CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102

2015
dbSNP: rs74315370
rs74315370
SDHB
C 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs747198089
rs747198089
SDHB
T 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs772551056
rs772551056
SDHB
T 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs786201316
rs786201316
SDHB
CC 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs786202732
rs786202732
SDHB
G 0.700 CausalMutation CLINVAR Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. 25371406

2015
dbSNP: rs786203251
rs786203251
SDHB
T 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs786203800
rs786203800
SDHB
T 0.700 CausalMutation CLINVAR Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. 25371406

2015
dbSNP: rs876659329
rs876659329
SDHB
T 0.700 GeneticVariation CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102

2015
dbSNP: rs876659330
rs876659330
SDHB
G 0.700 GeneticVariation CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102

2015
dbSNP: rs876660642
rs876660642
SDHB
G 0.700 CausalMutation CLINVAR Toward an improved definition of the genetic and tumor spectrum associated with SDH germ-line mutations. 25394176

2015
dbSNP: rs1131691061
rs1131691061
SDHB
T 0.700 CausalMutation CLINVAR Non-pheochromocytoma (PCC)/paraganglioma (PGL) tumors in patients with succinate dehydrogenase-related PCC-PGL syndromes: a clinicopathological and molecular analysis. 24096523

2014
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR Clinicopathological study of SDHB mutation-related pheochromocytoma and sympathetic paraganglioma. 24659481

2014