Gene: SDHC ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients. 27279923

2016
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients. 27279923

2016
dbSNP: rs786203457
rs786203457
SDHC
G 0.700 GeneticVariation CLINVAR Imaging work-up for screening of paraganglioma and pheochromocytoma in SDHx mutation carriers: a multicenter prospective study from the PGL.EVA Investigators. 23162105

2013
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013
dbSNP: rs786203457
rs786203457
SDHC
G 0.700 GeneticVariation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Long-delayed localization of a cardiac functional paraganglioma with SDHC mutation. 22868853

2012
dbSNP: rs786203457
rs786203457
SDHC
G 0.700 GeneticVariation CLINVAR Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells. 19332149

2009
dbSNP: rs786203457
rs786203457
SDHC
G 0.700 GeneticVariation CLINVAR Non-pheochromocytoma (PCC)/paraganglioma (PGL) tumors in patients with succinate dehydrogenase-related PCC-PGL syndromes: a clinicopathological and molecular analysis. 24096523

2014
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR Phenotypic variability and risk of malignancy in SDHC-linked paragangliomas: lessons from three unrelated cases with an identical germline mutation (p.Arg133*). 24423348

2014
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Polymyalgia rheumatica and vagal paraganglioma. 28412079

2017
dbSNP: rs587776653
rs587776653
SDHC
T 0.700 CausalMutation CLINVAR Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. 16249420

2005
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene. 16249420

2005
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes. 22703879

2012
dbSNP: rs786203457
rs786203457
SDHC
G 0.700 GeneticVariation CLINVAR Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients. 25025441

2014
dbSNP: rs786203457
rs786203457
SDHC
G 0.700 GeneticVariation CLINVAR Succinate dehydrogenase deficiency is rare in pituitary adenomas. 24625421

2014
dbSNP: rs786205147
rs786205147
SDHC
A 0.700 GeneticVariation CLINVAR Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review. 24886695

2014
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer. 23083876

2012
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Synchronous carotid body and thoracic paraganglioma associated with a germline SDHC mutation. 21106325

2011
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR The clinical phenotype of SDHC-associated hereditary paraganglioma syndrome (PGL3). 24758179

2014
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR The clinical phenotype of SDHC-associated hereditary paraganglioma syndrome (PGL3). 24758179

2014
dbSNP: rs1131691062
rs1131691062
SDHC
G 0.700 GeneticVariation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009