Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16969968
rs16969968
CHRNA5
0.010 GeneticVariation BEFREE In agreement with previous studies, the strongest determinant of tobacco dependence was rs16969968 with OR (95%CI) 1.32 (1.08-1.62) for A allele carriers vs. GG comparison (P=0.003). 28069549

2017
dbSNP: rs3733829
rs3733829
EGLN2 ; RAB4B-EGLN2
0.010 GeneticVariation BEFREE Except for rs3733829, association with tobacco dependence was confirmed for all other genetic variants. 28069549

2017
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.010 GeneticVariation BEFREE We found no association between smoking status and SNP rs4680 genotype nor did we find a significant association to the degree of tobacco dependence. 23288874

2013
dbSNP: rs16147
rs16147
NPY ; LOC107986777
0.010 GeneticVariation BEFREE Our results provide evidence for an involvement of the functionally relevant SNP rs16147 in the pathophysiology of tobacco dependence. 22584873

2012