Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs139883133
rs139883133
LMCD1 ; LMCD1-AS1
0.010 GeneticVariation BEFREE Moreover, overexpression of LMCD1 E135K mutation significantly promoted systemic lung metastasis in a murine tail vein injection model. 21996735

2012
dbSNP: rs121913227
rs121913227
BRAF
0.010 GeneticVariation BEFREE In melanoma, V600K mutations in comparison to other BRAF mutations were associated with more frequent brain (75% vs. 36.3%, p = 0.02) and lung metastases (91.6% vs. 47.7%, p = 0.007), and shorter time from diagnosis to metastasis and to death (19 vs. 53 months, p = 0.046 and 78 vs. 322 months, p = 0.024 respectively). 22039425

2011
dbSNP: rs121913499
rs121913499
IDH1
0.010 GeneticVariation BEFREE A somatic, heterozygous IDH1 c.C394T (p.R132C) mutation was identified in one human melanoma metastasis to the lung. 20603105

2010
dbSNP: rs121913529
rs121913529
KRAS
0.010 GeneticVariation BEFREE The codon 12 G12D mutation was found; the same mutation was evident in the primary cancer of the colon and in its liver and lung metastasis. 20213843

2010
dbSNP: rs767808984
rs767808984
NKX2-1 ; SFTA3 ; NKX2-1-AS1
0.010 GeneticVariation BEFREE The codon 12 G12D mutation was found; the same mutation was evident in the primary cancer of the colon and in its liver and lung metastasis. 20213843

2010
dbSNP: rs770374782
rs770374782
TP53
0.010 GeneticVariation BEFREE A somatic, heterozygous IDH1 c.C394T (p.R132C) mutation was identified in one human melanoma metastasis to the lung. 20603105

2010