Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2900174
rs2900174
PRB1 ; PRB2
G 0.800 GeneticVariation GWASCAT Genetic polymorphisms associated with pancreatic cancer survival: a genome-wide association study. 28470677

2017
dbSNP: rs763780
rs763780
IL17F
G 0.800 GeneticVariation GWASCAT Genetic polymorphisms associated with pancreatic cancer survival: a genome-wide association study. 28470677

2017
dbSNP: rs11141915
rs11141915
DAPK1
T 0.800 GeneticVariation GWASDB A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy. 22293537

2012
dbSNP: rs11141915
rs11141915
DAPK1
T 0.800 GeneticVariation GWASCAT A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy. 22293537

2012
dbSNP: rs2900174
rs2900174
PRB1 ; PRB2
G 0.800 GeneticVariation GWASCAT A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. 22142827

2012
dbSNP: rs2900174
rs2900174
PRB1 ; PRB2
G 0.800 GeneticVariation GWASDB A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. 22142827

2012
dbSNP: rs763780
rs763780
IL17F
G 0.800 GeneticVariation GWASCAT A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. 22142827

2012
dbSNP: rs763780
rs763780
IL17F
G 0.800 GeneticVariation GWASDB A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. 22142827

2012
dbSNP: rs121912578
rs121912578
SMAD4
0.800 GeneticVariation UNIPROT

dbSNP: rs121912578
rs121912578
SMAD4
C 0.800 CausalMutation CLINVAR

dbSNP: rs121913529
rs121913529
KRAS
0.740 GeneticVariation BEFREE Importantly, FGTI-2734 inhibited the growth of xenografts derived from four patients with pancreatic cancer with mutant KRAS (2 G12D and 2 G12V) tumors. 31227505

2019
dbSNP: rs121913529
rs121913529
KRAS
0.740 GeneticVariation BEFREE KRAS G12D point mutation plays an important role in the incidence of non-small-cell lung cancer (NSCLC) as well as colorectal cancer, pancreatic cancer and breast cancer. 30876538

2019
dbSNP: rs401681
rs401681
CLPTM1L
T 0.740 GeneticVariation GWASCAT Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. 29422604

2018
dbSNP: rs505922
rs505922
ABO
C 0.740 GeneticVariation GWASCAT Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. 29422604

2018
dbSNP: rs401681
rs401681
CLPTM1L
0.740 GeneticVariation BEFREE This meta-analysis suggests that T allele of CLPTM1L-telomerase reverse transcriptase rs401681 polymorphism is associated with an increased PC risk, especially among Chinese. 25284078

2015
dbSNP: rs401681
rs401681
CLPTM1L
0.740 GeneticVariation BEFREE A small number of common susceptibility loci have been identified for pancreatic cancer, one of which is marked by rs401681 in the TERT-CLPTM1L gene region on chromosome 5p15.33. 25940397

2015
dbSNP: rs401681
rs401681
CLPTM1L
0.740 GeneticVariation GWASCAT Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. 26098869

2015
dbSNP: rs505922
rs505922
ABO
0.740 GeneticVariation GWASCAT Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. 26098869

2015
dbSNP: rs505922
rs505922
ABO
0.740 GeneticVariation BEFREE This study provided evidence of SNP rs505922 C allele as a strong risk factor of cancer susceptibility, specifically for pancreatic cancer. 25656610

2015
dbSNP: rs401681
rs401681
CLPTM1L
0.740 GeneticVariation BEFREE Our data suggests that the T allele of rs401681 in CLPTM1L-TERT locus predisposes its carriers to pancreatic cancer, and further research into the function of CLPTM1L-TERT locus and its potential biological mechanism association may be warranted. 24577890

2014
dbSNP: rs401681
rs401681
CLPTM1L
0.740 GeneticVariation BEFREE These findings suggested that rs401681 C allele was a low-penetrance risk allele for the development of cancers of lung, bladder, prostate and basal cell carcinoma, but a potential protective allele for melanoma and pancreatic cancer. 23226346

2012
dbSNP: rs505922
rs505922
ABO
0.740 GeneticVariation BEFREE SNP rs505922, located within the first intron of the ABO gene, has been associated with the adenocarcinoma subtype of pancreatic cancer. 22642827

2012
dbSNP: rs121913529
rs121913529
KRAS
0.740 GeneticVariation BEFREE Oncogene-directed increased expression of Nrf2 is a new mechanism for the activation of the Nrf2 antioxidant program, and is evident in primary cells and tissues of mice expressing K-Ras(G12D) and B-Raf(V619E), and in human pancreatic cancer. 21734707

2011
dbSNP: rs505922
rs505922
ABO
0.740 GeneticVariation BEFREE Consistent with earlier reports showing a higher risk of PC for individuals with the non-O blood type, the previously reported protective allele (T) for rs505922 was found to be strongly correlated (r(2) = 0.96) with the O allele. 21306478

2011
dbSNP: rs401681
rs401681
CLPTM1L
T 0.740 GeneticVariation GWASCAT A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. 20101243

2010