|
rs1057518797
|
|
TAGGACG |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1556446493
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs730882222
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs754279998
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs770084716
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs771561387
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genotypic but not allelic association was observed for two markers, VEGF (-460 T>C) and PON1 (Arg192Gly) among NI diabetic CRI subjects.
|
18413200 |
2009 |
|
rs3782886
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjustment for clinical factors, kidney function was associated with BRAP rs3782886 and SPATA5L1 rs2467853 and the GRS for CKD that we developed was associated CKD.
|
29016630 |
2017 |
|
rs2467853
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjustment for clinical factors, kidney function was associated with BRAP rs3782886 and SPATA5L1 rs2467853 and the GRS for CKD that we developed was associated CKD.
|
29016630 |
2017 |
|
rs3093058
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among AASK participants, the rs3093058_T allele predicted higher CRP concentrations (P < 0.0001) but not CKD progression.
|
19965533 |
2010 |
|
rs76974938
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among polymorphisms identified in the present study, rs76974938 [C/T (D67N)] of C21orf59 and rs188780113 [G/A (R478C)] of ATG2A may be novel determinants of estimated glomerular filtration rate and chronic kidney disease or of the serum concentration of uric acid, respectively.
|
28410202 |
2017 |
|
rs188780113
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among polymorphisms identified in the present study, rs76974938 [C/T (D67N)] of C21orf59 and rs188780113 [G/A (R478C)] of ATG2A may be novel determinants of estimated glomerular filtration rate and chronic kidney disease or of the serum concentration of uric acid, respectively.
|
28410202 |
2017 |
|
rs1416580204
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the three described polymorphisms, only the RAGE Gly82Ser genotype frequency was significantly increased in the group with advanced nephropathy (11%) defined by a chronic renal failure compared to the three others groups: no nephropathy, 5%; incipient (microalbuminuria) 5%; established (macroalbuminuria), 2%) (P=0.04).
|
15803111 |
2005 |
|
rs2070600
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the three described polymorphisms, only the RAGE Gly82Ser genotype frequency was significantly increased in the group with advanced nephropathy (11%) defined by a chronic renal failure compared to the three others groups: no nephropathy, 5%; incipient (microalbuminuria) 5%; established (macroalbuminuria), 2%) (P=0.04).
|
15803111 |
2005 |
|
rs12313273
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among these polymorphisms, rs12313273 was found to be significantly associated with elevated serum calcium levels, which has been linked to increased risk of death in CKD patients.
|
24745010 |
2014 |
|
rs405509
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Among these polymorphisms, the -219G-->T polymorphism of APOE (rs405509) was most significantly associated with CKD in Japanese individuals with metabolic syndrome.
|
19056482 |
2009 |
|
rs6046
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An initial screen of allele frequencies by the chi-square test revealed that the 11496G-->A (Arg353Gln) polymorphism of F7 (rs6046) was significantly (false discovery rate <0.05) associated with the prevalence of MI in individuals with CKD.
|
19404551 |
2009 |
|
rs6066043
|
|
G |
0.700 |
GeneticVariation |
GWASDB |
An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka.
|
24351856 |
2014 |
|
rs699
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: risk of chronic renal failure. End-Stage Renal Disease Study Group.
|
10916074 |
2000 |
|
rs1267969615
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: risk of chronic renal failure. End-Stage Renal Disease Study Group.
|
10916074 |
2000 |
|
rs3779748
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Another SNP, rs3779748 in EYA1, was significantly associated with CKD at ARIC visit 1 (odds ratio per each T allele 1.22, p = 0.01), but only with eGFR and cystatin C in FHS.
|
18522750 |
2008 |
|
rs200340021
|
|
|
0.010 |
GeneticVariation |
BEFREE |
At the haplotype analysis, the combination of the X allele of Glu60X and the Thr allele of Thr83Ala showed a significantly increased risk of CKD (p < 0.05).
|
21859400 |
2011 |
|
rs11739136
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Common KCNMB1 gain-of-function variant Glu65Lys influences GFR, and 65Lys carriers exhibit not only elevated baseline GFR, but also more rapid GFR decline (and consequent development of renal failure) in CKD.
|
20861615 |
2010 |
|
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared to ESRD patients, non-CKD subjects were more likely to have T allele at SOD2 Val16Ala (p = 0.036) and CC genotype at PPAR-γ Pro12Ala (p = 0.028).
|
26881045 |
2016 |
|
rs1801282
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared to ESRD patients, non-CKD subjects were more likely to have T allele at SOD2 Val16Ala (p = 0.036) and CC genotype at PPAR-γ Pro12Ala (p = 0.028).
|
26881045 |
2016 |
|
rs1805192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared to ESRD patients, non-CKD subjects were more likely to have T allele at SOD2 Val16Ala (p = 0.036) and CC genotype at PPAR-γ Pro12Ala (p = 0.028).
|
26881045 |
2016 |