|
rs987401919
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion</b>: The results of the present study show that the mutation (CT+TT) at the rs987401919 and rs36071027 loci of <i>EBF1</i> and its interaction with smoking and drinking are risk factors for CAD, and that the mechanism may be related to the changes in blood pressure and blood lipid content.
|
29789399 |
2018 |
|
rs36071027
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<b>Conclusion</b>: The results of the present study show that the mutation (CT+TT) at the rs987401919 and rs36071027 loci of <i>EBF1</i> and its interaction with smoking and drinking are risk factors for CAD, and that the mechanism may be related to the changes in blood pressure and blood lipid content.
|
29789399 |
2018 |
|
rs4102217
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Our study demonstrated that the GC genotype and the recessive model of rs4102217 potentially increased CAD risk in some specific group.
|
30833365 |
2019 |
|
rs3777744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusions</b>: Our study indicates a significant association between the G-alleles of PPARD rs3777744 and rs3798343 and a decreased CAD risk.
|
30429241 |
2019 |
|
rs3798343
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusions</b>: Our study indicates a significant association between the G-alleles of PPARD rs3777744 and rs3798343 and a decreased CAD risk.
|
30429241 |
2019 |
|
rs822442
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> In 582 consecutive patients with stable coronary artery disease (CAD) or acute coronary syndrome (ACS) scheduled for PCI and treated with ASA and Clopidogrel, Prasugrel, or Ticagrelor, SNP analysis for rs12566888, rs2768759, rs41273215, rs3737224, and rs822442 was performed.
|
29867494 |
2018 |
|
rs12566888
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> In 582 consecutive patients with stable coronary artery disease (CAD) or acute coronary syndrome (ACS) scheduled for PCI and treated with ASA and Clopidogrel, Prasugrel, or Ticagrelor, SNP analysis for rs12566888, rs2768759, rs41273215, rs3737224, and rs822442 was performed.
|
29867494 |
2018 |
|
rs2768759
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> In 582 consecutive patients with stable coronary artery disease (CAD) or acute coronary syndrome (ACS) scheduled for PCI and treated with ASA and Clopidogrel, Prasugrel, or Ticagrelor, SNP analysis for rs12566888, rs2768759, rs41273215, rs3737224, and rs822442 was performed.
|
29867494 |
2018 |
|
rs41273215
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> In 582 consecutive patients with stable coronary artery disease (CAD) or acute coronary syndrome (ACS) scheduled for PCI and treated with ASA and Clopidogrel, Prasugrel, or Ticagrelor, SNP analysis for rs12566888, rs2768759, rs41273215, rs3737224, and rs822442 was performed.
|
29867494 |
2018 |
|
rs3737224
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Methods:</b> In 582 consecutive patients with stable coronary artery disease (CAD) or acute coronary syndrome (ACS) scheduled for PCI and treated with ASA and Clopidogrel, Prasugrel, or Ticagrelor, SNP analysis for rs12566888, rs2768759, rs41273215, rs3737224, and rs822442 was performed.
|
29867494 |
2018 |
|
rs7041
|
|
|
0.040 |
GeneticVariation |
BEFREE |
<b>Objectives</b>: The vitamin D binding protein encoded by the <i>GC</i> gene contains two single nucleotide polymorphisms (rs4588 and rs7041) that have been associated with disease outcome, these include periodontitis coronary heart disease and hypertension.
|
31559882 |
2019 |
|
rs9362054
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> The SNPs rs9362054 near the <i>CEP162</i> gene and rs4462262 near the <i>UBE2D1</i> gene were associated with DR (OR = 1.66, <i>p</i> = 0.001; OR = 1.37, <i>p</i> = 0.031; respectively), and rs12219125 near the <i>PLXDC2</i> gene was associated (suggestive) with CAD (OR = 2.26, <i>p</i> = 0.034).
|
31130920 |
2019 |
|
rs4462262
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> The SNPs rs9362054 near the <i>CEP162</i> gene and rs4462262 near the <i>UBE2D1</i> gene were associated with DR (OR = 1.66, <i>p</i> = 0.001; OR = 1.37, <i>p</i> = 0.031; respectively), and rs12219125 near the <i>PLXDC2</i> gene was associated (suggestive) with CAD (OR = 2.26, <i>p</i> = 0.034).
|
31130920 |
2019 |
|
rs12219125
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> The SNPs rs9362054 near the <i>CEP162</i> gene and rs4462262 near the <i>UBE2D1</i> gene were associated with DR (OR = 1.66, <i>p</i> = 0.001; OR = 1.37, <i>p</i> = 0.031; respectively), and rs12219125 near the <i>PLXDC2</i> gene was associated (suggestive) with CAD (OR = 2.26, <i>p</i> = 0.034).
|
31130920 |
2019 |
|
rs662799
|
|
|
0.070 |
GeneticVariation |
BEFREE |
<i>APOA5</i> SNPs rs662799 and rs651821 exhibited significant differences in genotype and allele distributions between patients with CAD and control subjects.
|
29866721 |
2018 |
|
rs651821
|
|
|
0.710 |
GeneticVariation |
BEFREE |
<i>APOA5</i> SNPs rs662799 and rs651821 exhibited significant differences in genotype and allele distributions between patients with CAD and control subjects.
|
29866721 |
2018 |
|
rs8259
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>BSG</i> rs8259 TT genotype was associated with a decreased risk of CHF (OR = 0.83, 95% CI = 0.72-0.96, <i>p</i> = 0.010), especially in patients with hypertension (OR = 0.80, 95% CI = 0.68-0.95, <i>p</i> = 0.011) and coronary heart disease (OR = 0.81, 95% CI = 0.69-0.96, <i>p</i> = 0.013) after adjustment for multiple cardiovascular risk factors.
|
28230811 |
2017 |
|
rs2291725
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>p</i> = 0.018 in subgroup analysis, individuals with higher BMI (≥24 kg/m<sup>2</sup>) had increased risk for CAD when carrying C/C at rs2291725 (OR' = 1.291, 95% CI' = 1.017-1.639, <i>p</i>' = 0.036).
|
29765988 |
2018 |
|
rs6882076
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>TIMD4</i> rs6882076 SNP Is Associated with Decreased Levels of Triglycerides and the Risk of Coronary Heart Disease and Ischemic Stroke.
|
31337960 |
2019 |
|
rs4646903
|
|
|
0.040 |
GeneticVariation |
BEFREE |
1.The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer.
|
19650794 |
2010 |
|
rs1800588
|
|
|
0.030 |
GeneticVariation |
BEFREE |
557 men aged 45-74 with stable coronary artery disease and 560 paired controls were genotyped for rs1800588.
|
23874450 |
2013 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
849 CAD patients undergoing revascularization (660 with CAC and 189 without CAC) were enrolled in a cohort study to test its association with cardiovascular events in CAD patients with and without CAC in a 3-year follow-up. rs1333049 was significantly associated with the incidence of cardiovascular events in non-target vessels in patients with CAC (hazard ratio = 1.44, 95%CI, 1.08-1.91, P = 0.012), but not in those without CAC.
|
24732910 |
2014 |
|
rs5985
|
|
|
0.030 |
GeneticVariation |
BEFREE |
9 (8%) Leu34Leu homozygous and 23 (20%) Val34Leu heterozygous subjects, had lower permeability by 23% in the CAD group compared with 81 (72%) patients with Val34Val genotype.
|
19784898 |
2009 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Coronary artery diseases (CAD) are influenced by multiple genes of modest effect as the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism, related to MTHFR activity and total plasma homocysteine (tHcy) concentration.
|
20530057 |
2010 |
|
rs611917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CAD association was replicated and/or verified for 4 loci: SORT1 rs611917 (p=1.7 × 10(-8)), APOA5 rs662799 (p=0.0014), LDLR rs1433099 (p=2.1 × 10(-7)), and APOE rs7412 (p=6.1 × 10(-13)).
|
23050023 |
2012 |