Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Ciliary neurotrophic factor null allele frequencies in schizophrenia, affective disorders, and Alzheimer's disease.
|
9342199 |
1997 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
It is concluded that the CNTF null mutation may be relevant to the aetiopathogenesis of schizophrenia in some patients, but further work is required to identify specifically the patient group for which it is important.
|
8856688 |
1996 |
Schizophrenia
|
0.390 |
Biomarker
|
disease |
PSYGENET |
The present study did not provide evidence for the association between the CNTF gene and schizophrenia or personality traits in the Japanese population.
|
16969278 |
2006 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that the polymorphisms at the DRD3, 5HTR2A, CNTF and BDNF gene loci are unlikely to make our sample more genetically susceptible to schizophrenia.
|
11343865 |
2001 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
We investigated the association between a null mutation in the ciliary neurotrophic factor (CNTF) gene and functional psychoses including schizophrenia and schizoaffective disorder.
|
9601653 |
1998 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Ciliary neurotrophic factor null mutation and schizophrenia in a Swedish population.
|
9285965 |
1997 |
Schizophrenia
|
0.390 |
Biomarker
|
disease |
PSYGENET |
Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial.
|
18303965 |
2008 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
LHGDN |
Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial.
|
18303965 |
2008 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Effect of a ciliary neurotrophic factor polymorphism on schizophrenia symptom improvement in an iloperidone clinical trial.
|
18303965 |
2008 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Our results did not provide evidence for the involvement of the null mutation of the CNTF gene in the development of schizophrenia.
|
9247976 |
1997 |
Schizophrenia
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
These results suggested that the variations at the NT3 and the CNTF genes do not influence the schizophrenia risk, but a role in the susceptibility of subgroups of the patients cannot be excluded.
|
15474906 |
2004 |
Schizophrenia
|
0.390 |
Biomarker
|
disease |
BEFREE |
The present study did not provide evidence for the association between the CNTF gene and schizophrenia or personality traits in the Japanese population.
|
16969278 |
2006 |
Schizophrenia
|
0.390 |
Biomarker
|
disease |
PSYGENET |
These results suggested that the variations at the NT3 and the CNTF genes do not influence the schizophrenia risk, but a role in the susceptibility of subgroups of the patients cannot be excluded.
|
15474906 |
2004 |
Schizophrenia
|
0.390 |
Biomarker
|
disease |
PSYGENET |
Our results suggest that the polymorphisms at the DRD3, 5HTR2A, CNTF and BDNF gene loci are unlikely to make our sample more genetically susceptible to schizophrenia.
|
11343865 |
2001 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
PSYGENET |
No sign of CNTF-induced toxicity was observed; however, depression occurred in three subjects after removal of the last capsule, which may have correlated with the lack of any future therapeutic option.
|
15585112 |
2004 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
PSYGENET |
These results call in question the hypothesis that either BDNF or CNTF can be used as molecular markers for depression or late onset depression in the elderly.
|
16797081 |
2006 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
BEFREE |
These results call in question the hypothesis that either BDNF or CNTF can be used as molecular markers for depression or late onset depression in the elderly.
|
16797081 |
2006 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
PSYGENET |
Associations between AD and/or depression to gene polymorphisms APO E (epsilon4), choline acetyltransferase (ChAT) 4G to A, serotonin-transporter gene promoter-length, dopamine-D4-receptor, ciliary-neurotrophic-factor-null mutation and brain-derived neurotrophic factor (C270T) and to various known factors were analyzed.
|
18603262 |
2009 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
BEFREE |
This study reveals a novel CNTF-mediated mechanism in stress-induced depressive-like behavior and points to opportunities for sex-specific treatments for depression, e.g. progesterone in females and CNTF-stimulating drugs in males.
|
30299260 |
2019 |
Mental Depression
|
0.320 |
Biomarker
|
disease |
PSYGENET |
These data imply that endogenous CNTF plays a pivotal role for the structural maintenance of hippocampal functions and thus has an important impact on the modulation of affective behavior in rodent models of anxiety and depression.
|
22266927 |
2012 |
Depressive disorder
|
0.320 |
Biomarker
|
disease |
BEFREE |
This study reveals a novel CNTF-mediated mechanism in stress-induced depressive-like behavior and points to opportunities for sex-specific treatments for depression, e.g. progesterone in females and CNTF-stimulating drugs in males.
|
30299260 |
2019 |
Depressive disorder
|
0.320 |
Biomarker
|
disease |
PSYGENET |
These data imply that endogenous CNTF plays a pivotal role for the structural maintenance of hippocampal functions and thus has an important impact on the modulation of affective behavior in rodent models of anxiety and depression.
|
22266927 |
2012 |
Depressive disorder
|
0.320 |
Biomarker
|
disease |
PSYGENET |
Associations between AD and/or depression to gene polymorphisms APO E (epsilon4), choline acetyltransferase (ChAT) 4G to A, serotonin-transporter gene promoter-length, dopamine-D4-receptor, ciliary-neurotrophic-factor-null mutation and brain-derived neurotrophic factor (C270T) and to various known factors were analyzed.
|
18603262 |
2009 |
Depressive disorder
|
0.320 |
Biomarker
|
disease |
PSYGENET |
No sign of CNTF-induced toxicity was observed; however, depression occurred in three subjects after removal of the last capsule, which may have correlated with the lack of any future therapeutic option.
|
15585112 |
2004 |
Depressive disorder
|
0.320 |
Biomarker
|
disease |
PSYGENET |
These results call in question the hypothesis that either BDNF or CNTF can be used as molecular markers for depression or late onset depression in the elderly.
|
16797081 |
2006 |