|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
HPO |
|
|
|
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
(3) The COMT genotype is related to performance on prefrontal cortex-dependent tasks and may contribute to the deficit in prefrontal-dependent memory processes in SPD as it does in schizophrenia.
|
16691129 |
2006 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
(3) The COMT genotype is related to performance on prefrontal cortex-dependent tasks and may contribute to the deficit in prefrontal-dependent memory processes in SPD as it does in schizophrenia.
|
16691129 |
2006 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility.
|
14754787 |
2004 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
LHGDN |
Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility.
|
14754787 |
2004 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Catechol O-methyltransferase polymorphism and eye tracking in schizophrenia: a preliminary report.
|
15569909 |
2004 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: a large-scale association study plus meta-analysis.
|
15652872 |
2005 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Catechol-O-methyltransferase (COMT) is a strong candidate gene for schizophrenia and cognitive functions disrupted in this disorder.
|
16043133 |
2005 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
COMT Association Data in Schizophrenia: New Caveats.
|
16899231 |
2006 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Catechol-O-methyltransferase (COMT) val(108/158)met (rs4680) is thought to affect dopamine regulated prefrontal cortical activity during working memory (WM) tasks, and to weakly increase risk for developing schizophrenia.
|
17707347 |
2008 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
COMT dysfunction has been related to schizophrenia and breast cancer.
|
18064318 |
2007 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
COMT gene is a logical candidate gene for schizophrenia.
|
18407467 |
2008 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT val(158)met genotype and smooth pursuit eye movements in schizophrenia.
|
19647329 |
2009 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT Val158Met polymorphism in relation to activation and de-activation in the prefrontal cortex: A study in patients with schizophrenia and healthy subjects.
|
20398774 |
2010 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT Val(158)Met polymorphism was studied with ARMS-PCR method in 99 outpatients with schizophrenia.
|
20570494 |
2010 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT haplotype analyses in Malaysians with schizophrenia.
|
21872942 |
2012 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Catechol-O-methyltransferase (COMT) genotype biases neural correlates of empathy and perceived personal distress in schizophrenia.
|
22901597 |
2013 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT and MTHFR polymorphisms interaction on cognition in schizophrenia: an exploratory study.
|
23353103 |
2013 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Catechol-O-methyltransferase (COMT), a positional candidate gene for schizophrenia, resides within the 22q11.2 region.
|
24534796 |
2014 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Catechol-O-methyltransferase (COMT) is a candidate susceptibility gene for schizophrenia that is involved in the regulation of dopamine in the prefrontal cortex.
|
25722988 |
2015 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT genotype and response to cognitive remediation in schizophrenia.
|
26255563 |
2015 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT-Val is a putative risk factor in schizophrenia, which is characterized by disordered prefrontal function.
|
26649915 |
2016 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
COMT val158met polymorphism and molecular alterations in the human dorsolateral prefrontal cortex: Differences in controls and in schizophrenia.
|
27021555 |
2016 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
A common functional polymorphism, G1947A, of the catechol-O-methyltransferase (COMT) enzyme has gained interest in schizophrenia research because of its critical involvement in cortical dopamine catabolism and frontal lobe function.
|
12842307 |
2003 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
A common functional polymorphism, Val108/158Met (rs4680), and haplotypes rs737865-rs4680-rs165599 in the Catechol-O-methyltransferase gene (COMT) have been extensively examined for association to schizophrenia; however, results of replication studies have been inconsistent.
|
19329282 |
2009 |