|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A total of 1,110 patients diagnosed with sepsis were retrospectively analyzed to identify response patterns for risk stratification of routine parameters measured at the peak level of C-reactive protein.
|
31275752 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In terms of the diagnostic accuracy of C-reactive protein (CRP) for sepsis, the overall area under the summary receiver operator characteristic (SROC) curve was 0.73 (95% confidence interval [CI], 0.69-0.77), with a sensitivity and specificity of 0.80 (95% CI, 0.63-0.90) and 0.61 (95% CI, 0.50-0.72) respectively, and the DOR was 6.89 (95% CI, 3.86-12.31).
|
30417415 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Toward Early Diagnosis of Late-Onset Sepsis in Preterm Neonates: Dual Magnetoimmunosensor for Simultaneous Procalcitonin and C-Reactive Protein Determination in Diagnosed Clinical Samples.
|
31305070 |
2019 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Comparison of markers of sepsis revealed C-reactive protein, interleukin-6 level to be significantly higher and pH, pCO<sub>2</sub>, HCO<sub>3,</sub> and base excess values to be significantly lower in newborns with sepsis compared healthy controls (p<0.01).
|
30858952 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The C-reactive protein (CRP)/albumin ratio has been regarded as an outcome predictor in patients with cancer and sepsis.
|
31486619 |
2019 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CONCLUSIONS The levels of plasma BNP and cTnI are associated with the severity of sepsis in pediatric patients, and were positively correlated with CRP and TNF-alpha levels, which provides a novel strategy for the early diagnosis and evaluation of sepsis in pediatric patients.
|
30956276 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
When integrated in a scoring system, neutrophil CD64 in combination with C-reactive protein (CRP) and SOFA score showed a diagnostic accuracy of 0.93 for sepsis and significantly predicted increased mortality risk.
|
31584643 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
These patients had CRP concentrations of <31.9 mg/L, the determined cut-off for CRP concentrations in a large cohort of apparently healthy individuals in the community (n = 17,214, upper limit of mean + 3 standard deviations).By processing the electronic medical records, we found 2724 patients with a diagnosis of sepsis, 476 of whom had an admission CRP concentration of <31.9 mg/L.
|
30633182 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The prognostic value of bioscore and SOFA was similar for predicting 90-day mortality.<b>Conclusions:</b> The new bioscore formed by combination of CRP, PCT and SOFA score may be useful in early diagnosis of sepsis.
|
31687850 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Several lines of evidences suggest that PSP has a higher diagnostic performance for the identification of sepsis than procalcitonin and C-reactive protein, and a strong prognostic value to predict unfavorable outcome at admission to intensive care unit.
|
30672312 |
2019 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Median DNI (16.3 vs 1,4) and CRP (6.8 vs 0,03 mg/dl) were significantly higher in sepsis group.
|
30771742 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
(2) CRP and WBC were unable to predict sepsis (P > 0.05 for all), while PCT and NEU% could predict sepsis with areas under the curve (AUC) of 0.838 and 0.691, respectively (P < 0.05 for all).
|
30805753 |
2019 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Mechanical ventilation, white blood cell (WBC) counts, C-reactive protein (CRP) and lactate levels, maximum 24-h APACHE-II scores, and AGP concentrations were significantly higher upon admission in patients with sepsis who died.
|
31309103 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The area under the ROC curve (AUC) of HBP (cut-off ≥28.1 ng/mL) was 0.893 for sepsis which was higher than those of PCT (0.856) for a cut-off ≥2.05 ng/mL and of CRP (0.699) for a cut-off ≥151.9 mg/L.
|
31015272 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The application of PCT to predict local infection in patients with T2DM was identified to be inferior to CRP, but its ability to predict sepsis was concluded to be the best when compared with CRP, white blood cell count and neutrophil percent.
|
31258707 |
2019 |
|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Age (P = 0.24), surgical status (P = 0.95), or sepsis (P = 0.77) did not influence the CRP course.
|
29438222 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The prediction of NLR, an easy, inexpensive, and rapid method, along with CRP in the neonatal period for diagnosis of sepsis, will be more effective in detecting culture-proven sepsis and in decreasing unnecessary antibiotherapy.
|
29055117 |
2018 |
|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Recent National Institute for Health and Care Excellence (NICE) CG149 guidelines suggest considering performing a lumbar puncture (LP) to investigate for meningitis in early-onset sepsis in a neonate when a C-reactive protein (CRP) level >10mg/L, but the evidence for this recommendation is poorly defined.
|
30509228 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Between 2012 and 2015, PCT use among sepsis discharges increased six-fold while lactate and CRP use remained unchanged.
|
30332466 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Positive post-test probability for any combinations of simultaneously analyzed CRP, PCT and CD64 showed improved diagnostic accuracy for sepsis.
|
28898742 |
2018 |
|
Septicemia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We evaluated the impact of an automatic stop order (ASO) and C-reactive protein (CRP) on the duration of antibiotics and level of intervention in infants screened for early-onset sepsis who had negative cultures.
|
28155332 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Neonates with clinical manifestations of sepsis who exhibited two positive screening tests (microESR, C- reactive protein, band cell count) were included and randomized into no zinc and zinc group.
|
28891027 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
CRP, IL-6 and PCT are applicable to the differential diagnosis of sepsis and differentiating the sepsis induced by Gram-negative bacteria from Gram-positive bacteria.
|
30004393 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study assessed the ability of mid-regional proadrenomedullin (MR-proADM) in comparison to conventional biomarkers (procalcitonin (PCT), lactate, C-reactive protein) and clinical scores to identify disease severity in patients with sepsis.
|
29562917 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The area under the curve (AUC) for differentiating infants with culture-proven sepsis from controls was 0.999 compared with an AUC of 1 for CRP.
|
29605824 |
2018 |