CRP, C-reactive protein, 1401

N. diseases: 1483; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE The aim of the present study is to determine the association of melatonin hormone level on CRP, Total Antioxidant Status, Leukocyte, Procalcitonin, and Malondialdehyde, all acute phase reactants in the dark and light cycle of rats with sepsis model. 31806239 2020
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE CRP analyzed on days 1 and 3, subsequently patients were identified in two groups: sepsis (<i>n</i> = 28) and no-sepsis (<i>n</i> = 67).<b>Results:</b> MPV was significantly higher on both day 1 (10.23 ± 0.92) fl and day 3 (10.77 ± 1.16) fL in the sepsis group compared with no-sepsis (8.11 ± 0.29) fl and (8.53 ± 0.42) fl, respectively. 29886794 2020
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE PCT correlated with C-reactive protein as a biomarker for sepsis (P < 0.001), but not with other biomarkers. 31635838 2020
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE Predictive value of C-reactive protein and NT-pro-BNP levels in sepsis patients older than 75 years: a prospective, observational study. 31214930 2020
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE <b>Conclusions:</b> Majority of postpartum cervical discharge, fever, and increased CRP levels do not represent morbid infections and/or sepsis. 29671364 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 GeneticVariation disease BEFREE Death was the primary outcome in only one study and a survival benefit was not observed in the subset specified as sepsis (10 RCTs; RR, 0.94; 95% CI, 0.85-1.03; I<sup>2</sup> = 0%), those without industry sponsorship (nine RCTs; RR, 0.98; 95% CI, 0.87-1.10; I<sup>2</sup> = 0%), high PCT-guided algorithm adherence (five RCTs; RR, 0.93; 95% CI, 0.71-1.22; I<sup>2</sup> = 0%), and PCT-guided algorithms without C-reactive protein (eight RCTs; RR, 0.96; 95% CI, 0.87-1.06; I<sup>2</sup> = 0%). 30772386 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE At the time of the admission, presepsin, procalcitonin, C-reactive protein, and IL-8 were significantly higher in the sepsis group. 31651475 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE The objectives of this study were to study the clinical and biochemical profile of neonates with sepsis and to evaluate the diagnostic role of presepsin and its comparison with C-reactive protein (CRP) and Procalcitonin (PCT). 29577181 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Kinetic studies of PCT and CRP can improve sensitivity and accuracy when evaluating the prognosis of patients with sepsis and those with septic shock. 30656987 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE There were significantly higher serum levels of CRP among late onset versus early onset sepsis group with significantly higher serum levels of hsCRP and presepsin among early onset compared with the late onset sepsis group (p < 0.05 for all). 29895470 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 GeneticVariation disease BEFREE We performed a systematic review and meta-analysis to evaluate the diagnostic accuracy of neutrophil CD64, comparing it with C-reactive protein (CRP) and procalcitonin (PCT) for the diagnosis of infection in adult patients with septic syndrome, based on sepsis-2 criteria. 30623257 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Procalcitonin (PCT) and C reactive protein (CRP) are inflammatory blood markers that have been proven useful to support diagnosis and monitoring of (bacterial) respiratory tract infections and sepsis. 31401614 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Significant differences in NLCR values were observed between sepsis and non-sepsis patients (15.3 [10.8-38.2] (median [interquartile range] vs. 9.3 [6.2-14.5]; P<0.001), as well as for CRP level, PCT level and lymphocyte count. 30811475 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Detection of serum procalcitonin and hypersensitive C-reactive protein in patients with pneumonia and sepsis. 30334408 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE The present study demonstrated that compared to CRP and PCT, PSEP is a superior biomarker for the postmortem differentiation of sepsis and that a concentration >1250 pg/mL is highly likely to indicate sepsis within 96 h of death. 30954003 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 GeneticVariation disease BEFREE Burned BSA ≥25% and CRP ≥6 mg/dL were risk factors for developing sepsis in pediatric burn patients. 31589562 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE The results of this study suggest that IL-6 is better than PCT and CRP in predicting the treatment success in predominantly non-surgical sepsis in the first 48-72 h. 30760225 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Procalcitonin (PCT) and C-reactive protein (CRP) are commonly used biomarkers, but their diagnostic advantage for neonatal early-onset (EOS) or late-onset (LOS) sepsis is controversial. 30926891 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Several serum-based biomarkers such as C-reactive protein, lactate, presepsin, and cytokines, such as interleukin-1 (IL-1), and IL-6 have been evaluated as early indicators of sepsis but none have been proven sensitive and/or specific enough to make a definitive diagnosis. 31323346 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE It was not inferior to other laboratory values, including activated partial thromboplastin time (AUC: 0.729), C-reactive protein (AUC: 0.727), albumin (AUC: 0.834), prothrombin time (AUC: 0.816), and creatinine (AUC: 0.837) known to be associated with sepsis. 30985959 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Presepsin and resistin had similar performance as CRP and PCT for the diagnosis of infection (best cut-off of 1444 pg/ml and 20 ng/ml, respectively) and sepsis. 31221548 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE The aims of the present meta-analysis were to assess the overall diagnostic accuracy of presepsin in pediatric sepsis and compare it to those for C-reactive protein (CRP) and procalcitonin (PCT). 31470804 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE SOFA scores at POD 1-7 can effectively predict the incidence of sepsis and 30-day mortality in liver transplant patients on the basis of CRP and PCT. 30721450 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Median CRP and PCT were highly and significantly increased during sepsis/SIRS and bacteremia (17.24 mg/dl ; 6.30 ng/ml; p < 0.0001 vs. prior values), graft rejection (14.73 mg/dl ; 3.20 ng/ml; p < 0.0001), and liver GvHD (6.88 mg/dl ; 2.29 ng/ml; p < 0.01). 31446489 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Circulating concentrations of CRP, PCT, interleukin (IL)-10 and IL-1 receptor antagonist (IL-1Ra) were significantly higher in patients with sepsis, with IL-10 identified as the best biomarker in differentiating sepsis from SIRS. 31125901 2019