|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Overall, this suggests that our results failed to support the hypothesis that IL6, CRP and BDNF are directly involved in the therapeutic mechanism of NAC in depression.
|
28318471 |
2017 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Sex Difference in the Association between High-sensitivity C-reactive Protein and Depression: The 2016 Korea National Health and Nutrition Examination Survey.
|
30760746 |
2019 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study aimed to examine the serum levels of interleukin-6 (IL-6) and C-reactive protein (CRP) in MDD patients to find out their association with depression.
|
30899619 |
2019 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The present study examines associations between peripheral CRP concentrations and threat-related amygdala activity, a neural biomarker of depression and anxiety risk, in a sample of 172 young adult undergraduate students.
|
28183031 |
2017 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Relationships between CRP and KYNA with some hippocampal subfield volumes in MDD patients suggest that this inflammatory signature may be associated with reduced hippocampal subfield volumes in depression.
|
29787958 |
2018 |
|
Depressive disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Logistic regression analyses revealed that menstrual status, chronic diseases, serum inflammatory factors (CRP, IL-6 and TNF-α) and BDNF levels had independent predictive values for depression in patients with perimenopausal syndrome (P<0.05).
|
29849779 |
2018 |
|
Depressive disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
IgM responses to NO-adducts and OSEs, especially malondialdehyde and myristic acid, and C-reactive protein (CRP) were inversely associated with TRYCAT pathway activity, whilst a lifetime depression and Pseudomonas putida were positively associated.
|
28600633 |
2017 |
|
Depressive disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Findings across the literature suggest that functional allelic variants of genes for interleukin-1beta (IL)-1β, tumor necrosis factor-alpha (TNF-α) and C-reactive protein (CRP), as well as genetic variations affecting T-cell function, may increase the risk for depression.
|
22580182 |
2013 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The associations between baseline log CRP and depression response and remission were also assessed.
|
29654412 |
2019 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Role of IL-8, CRP and epidermal growth factor in depression and anxiety patients treated with mindfulness-based therapy or cognitive behavioral therapy in primary health care.
|
28501736 |
2017 |
|
Depressive disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our finding may raise new evidence that genetically increased serum CRP level through SNPs variation is likely to induce family inherited depression.
|
30048584 |
2018 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The depression sum-score was related to both IL-6 and CRP before, and only to IL-6 after covariate adjustment.
|
31615595 |
2019 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Meta-analyses of studies that allowed formal Mendelian randomisation were identified for C reactive protein (and did not support a causal effect), and were lacking for exercise, diabetes, and depression.
|
19892791 |
2009 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Is the Relationship between Depression and C Reactive Protein Level Moderated by Social Support in Elderly?-Korean Social Life, Health, and Aging Project (KSHAP).
|
29422922 |
2018 |
|
Depressive disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These effects were fully attenuated by five serum proteins: AGE: Insulin-like Growth Factor-Binding Protein 2 (IGF-BP2), Epidermal Growth Factor Receptor 1 (EGFR); Depression: Resistin; Gender: Thrombopoeitin (THPO); APOE: C-Reactive Protein (CRP).
|
31665233 |
2019 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Severity of depression is correlated with elevated CRP but not with IL-6.
|
28558901 |
2017 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
There was no difference in TNF-α (p = 0.351) and CRP (p = 0.05) between those with depression and controls.
|
30104698 |
2018 |
|
Depressive disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We have examined whether longitudinal patterns of inflammation, based on three CRP measurements from childhood to early-adulthood, are associated with the risk of depression in early-adulthood in the Avon Longitudinal Study of Parents and Children, a prospective birth cohort.
|
31707310 |
2020 |
|
Depressive disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Numerous studies have shown associations between an on-going depression and elevated serum levels of the acute-phase reactant C-reactive protein (CRP).
|
23277135 |
2013 |
|
Depressive disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Depression and anxiety both associate with serum level of hs-CRP: A gender-stratified analysis in a population-based study.
|
28419913 |
2017 |
|
Depressive disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Here we present evidence suggestive of interaction with childhood maltreatment for novel loci in IL-6 (rs1818879) and CRP (rs3093077), increasing risk of depression.
|
28867280 |
2018 |
|
Depressive disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our results show that CHD patients with depression had higher levels of CRP, IL-6 gene expression, and VEGF compared with CHD non-depressed, as well as lower plasma and saliva cortisol levels.
|
25683698 |
2015 |
|
Depressive disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Fatigued bereaved individuals (33%; SF-36 energy/vitality score 0-45) had significantly higher CRP levels (p < .05) as compared to non-fatigued bereaved individuals and reported higher levels of pain (p < .001), greater stress (p < .001), depression (p < .001), and sleeping problems (p < .001), as well as poorer social functioning (p < .001) and general health (p < .001) than those in the non-fatigued group.
|
30097134 |
2018 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
When stratifying by zygosity, significant associations from IL-6 to depression were only seen in monozygotic twins, but associations from depression to CRP were more robust in dizygotic twins, which implies that genetic factors may play a role in this association.
|
30394311 |
2019 |
|
Depressive disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
A longitudinal cohort study was performed with repeated measures of pain (0-10 numeric rating scale) and evaluation of other self-reported symptoms (Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, and Fatigue Severity Score), daily functioning (Lawton Instrumental Activities of Daily Living Scale), quality of life (EQ-5D-3L), knee function (KSS Knee and Function Score), perioperative and clinical characteristics (e.g. surgery duration, brand of implant, comorbidities), biochemical parameters (haemoglobin, C-reactive protein, creatinine), and patient satisfaction (20-item scale).
|
28916991 |
2018 |