AGRP, agouti related neuropeptide, 181

N. diseases: 233; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa
0.070 Biomarker disease LHGDN Plasma agouti-related protein levels in women with anorexia nervosa. 16904835 2006
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa
0.070 GeneticVariation disease LHGDN Mutation analysis of the agouti related protein promoter region and the melanocortin-3 receptor in anorexia nervosa patients. 16314751 2005
CUI: C0003467
Disease: Anxiety
Anxiety
0.010 AlteredExpression disease BEFREE Mechanistically, we found that chemogenetic activation of Agrp neurons reduced anxiety in fed mice, and inactivation of Agrp neurons reduced fasting-induced anxiolytic effects. 30850579 2019
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.010 AlteredExpression group BEFREE Mechanistically, we found that chemogenetic activation of Agrp neurons reduced anxiety in fed mice, and inactivation of Agrp neurons reduced fasting-induced anxiolytic effects. 30850579 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.010 Biomarker disease BEFREE The associations between AHA score and markers of subclinical atherosclerosis in ART and non-ART groups were similar in magnitude. 31834929 2020
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.010 Biomarker disease BEFREE The associations between AHA score and markers of subclinical atherosclerosis in ART and non-ART groups were similar in magnitude. 31834929 2020
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders
0.010 Biomarker disease BEFREE This is the first large genetic association to concurrently examine the genotype of individuals with ASD in relation to their exposure to ART versus natural conception, and it adds reassuring evidence to the argument that ART does not increase the risk of ASD. 24842673 2014
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.010 Biomarker disease BEFREE ART proposes that there are often dynamic breakdowns of tonic control in mental disorders such as autism, where vigilance remains high, and medial temporal amnesia, where vigilance remains low. 29163063 2017
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.010 Biomarker group BEFREE Current guidelines on the management of women with SCH and/or thyroid autoimmunity undergoing ART cycles will be presented in this review. 31532314 2019
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections
0.010 Biomarker group BEFREE In this study, we aimed to quantify the effects of immediate versus deferred ART on the risk of severe bacterial infection in people with high CD4 cell counts in a preplanned analysis of the START trial. 28063815 2017
CUI: C0085166
Disease: Bacterial Vaginosis
Bacterial Vaginosis
0.010 Biomarker disease BEFREE The majority (96%) was on ART and had undetectable (85%) plasma HIV RNA (<40 copies/mL).BV was diagnosed in 32%. 28569142 2017
Behavioral and psychological symptoms of dementia
0.010 GeneticVariation phenotype BEFREE Efavirenz related neuropsychiatric symptoms are common among Ugandan HIV patients receiving ART and is mainly predicted by higher efavirenz plasma concentrations and CYP2B6 genotype but not by rifampicin based anti-TB co-treatment. 23734829 2013
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.010 AlteredExpression disease BEFREE Serum agouti-related protein (AgRP) levels in bipolar disorder: Could AgRP be a state marker for mania? 29172096 2018
CUI: C2267227
Disease: Bulimia Nervosa
Bulimia Nervosa
0.010 GeneticVariation disease BEFREE AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018). 24831852 2014
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders
0.010 GeneticVariation group BEFREE Low to moderate alcohol and caffeine intakes in the year prior to infertility treatment were not related to ART outcomes. 28854726 2017
CUI: C0349534
Disease: Carcinoma of anal margin
Carcinoma of anal margin
0.010 GeneticVariation disease BEFREE Scans from 26 patients participating in the ART trial (full title: Anal squamous cell carcinoma: Investigation of functional imaging during chemoRadioTherapy), a single center observational study with FDG PETCT prior to radiotherapy and at fraction 8-10 of concurrent chemoradiation were analysed. 31506182 2020
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.010 Biomarker group BEFREE Plasma glycomics predict cardiovascular disease in patients with ART-controlled HIV infections. 30183373 2019
CUI: C0333519
Disease: Caries (morphologic abnormality)
Caries (morphologic abnormality)
0.010 Biomarker disease BEFREE SDF requires much less chair-time and have similar results as ART in arresting caries lesion, anxiety, adverse effects, aesthetic perception and quality of life. 31279925 2019
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis
0.010 GeneticVariation disease BEFREE We evaluated the prevalence and risk factors related to carotid atherosclerosis among well-suppressed HIV-infected adults receiving long-term ART from Thailand. 31530175 2020
CUI: C0007684
Disease: Central Nervous System Infection
Central Nervous System Infection
0.010 GeneticVariation group BEFREE In this study, we examined HIV-1 variants in ART-naïve children aged three years or younger to determine viral genotypes and phenotypes associated with HIV-1 subtype C pediatric CNS infection. 23300446 2012
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.010 Biomarker disease BEFREE Amelanotic (Ab) melanoma (with the inhibited melanogenesis, higher malignancy) and SHSY5Y neuroblastoma (with cholinergic DC cells) were especially sensitive to ART action. 30367436 2019
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker disease BEFREE The data that are available for malignancies seem reassuring, while results on neurodevelopmental health are more equivocal with a possible association between ART and cerebral palsy. 30753453 2019
CUI: C2733158
Disease: Cerebral Small Vessel Diseases
Cerebral Small Vessel Diseases
0.010 GeneticVariation group BEFREE The increasing risk of CSVD was not associated with exposure to any ART class. 31107300 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.010 Biomarker group BEFREE Here, we present and evaluate a novel and affordable augmented reality system (Augmented Reflection Technology, ART) in combination with a validated mirror therapy protocol for upper limb rehabilitation after stroke. 28478736 2017
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma
0.010 AlteredExpression disease BEFREE Competition assays were used to measure the relative binding affinities of engineered AgRP peptides for integrin receptors expressed on the surface of U87MG glioblastoma cells. 20124048 2010