EPO, erythropoietin, 2056

N. diseases: 646; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia resulting from the reduced expression of erythropoietin (EPO) is a common complication of patients with chronic kidney diseases (CKD). 28625716 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human High dose of erythropoietin in management of interferon/ribavirin induced anemia. 18265628 2007
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE These results suggest that impaired production of Epo may be a direct effect of HIV-1 infection possibly contributing to anemia in AIDS. 8390370 1993
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Accelerating Epo production in hepatocytes is one plausible therapeutic strategy for treating anemia caused by kidney diseases. 26012551 2015
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human Testosterone membrane-initiated action in breast cancer cells: Interaction with the androgen signaling pathway and EPOR. 20189893 2010
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE The recombinant form of human erythropoietin is in clinical use for the prevention and treatment of anemia that is associated with cancer and its treatment with chemoradiation therapy. 15467711 2005
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE The transplantation of polymer encapsulated myoblasts genetically engineered to secrete erythropoietin (Epo) may obviate the need for repeated parenteral administration of recombinant Epo as a treatment for chronic renal failure, cancer or AIDS-associated anemia. 10326023 1998
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE Proinflammatory cytokine, mainly IL-6, which are released by both tumor and immune cells, play a pivotal action in CRA etiopathogenesis: they promote alterations in erythroid progenitor proliferation, erythropoietin (EPO) production, survival of circulating erythrocytes, iron balance, redox status, and energy metabolism, all of which can lead to anemia. 30294279 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Hypoxia-regulated system of Epo gene expression constructed by fusing Epo to the HRE/CMV promoter and delivered by plasmid intramuscular injection may provide a long-term and stable Epo expression and secretion in vivo to correct the anemia in adenine-induced uremic rats. 22990115 2012
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human Testosterone membrane-initiated action in breast cancer cells: Interaction with the androgen signaling pathway and EPOR. 20189893 2010
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human Patients with esophagogastric adenocarcinoma who experienced anemia (hemoglobin < 12 g/dL) during neoadjuvant treatment received erythropoietin 10,000 IE subcutaneously three times a week. 16798232 2006
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Specific binding of erythropoietin to spleen cells infected with the anemia strain of Friend virus. 6095306 1984
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE The anemia of the newborn induces erythropoietin expression in the developing mouse retina. 20463184 2010
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Our findings indicate that combination Fe + EPO therapy is effective in partially reversing ICU anemia when administered after the phase of acute inflammation. 28452907 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Erythropoiesis-stimulating agents (ESAs) are man-made forms of erythropoietin used in the treatment of anemia. 30097240 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Erythropoietin is used in a few patients with anaemia to overcome functional iron deficiency, and blood transfusion is being restricted to refractory cases or acute life-threatening situations. 30544934 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human We compared blood pressure after three different methods of partial correction of anemia in hemodialysis patients with similar baseline hematocrits (erythropoietin n = 12, intravenous iron alone n = 10, androgens n = 9). 1516988 1992
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE The cost of treating ribavirin-induced anemia in hepatitis C: the impact of using recombinant human erythropoietin. 17559739 2007
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE The therapy for anemia evaluated in the most studies was erythropoietin-stimulating agents (77.7% of studies). 30100259 2019
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Iron deficiency is a common etiology of anemia that causes suboptimal response to erythropoietin therapy in hemodialysis (HD) patients. 31679114 2020
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Erythropoiesis-stimulating agents, such as recombinant human erythropoietin, are commonly used for the treatment of anemia in patients with chronic kidney disease (CKD). 29296077 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Epoetin-α reduced RBC transfusions and increased the time-to-first-transfusion compared with placebo.Thus, epoetin-α significantly improved anemia outcomes in low-risk MDS. 29895954 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE The effectiveness of biosimilar epoetin alfa (Binocrit<sup>®</sup>, Sandoz) to correct anemia in lower-risk MDS patients has also been demonstrated in a retrospective, single-center, observational study. 31005849 2019
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Recombinant human erythropoietin (Epo) supplementation is one of the methods for treating anemia. 27903235 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Erythropoietin (EPO) has been used to treat anemia of cancer patients, because it stimulates erythropoiesis. 28247960 2017